caa a22 4500 465767419 CHVBK 20180323111918.0 cr unu---uuuuu 170327e19900201xx s 000 0 eng 10.1007/BF00296120 doi (NATIONALLICENCE)springer-10.1007/BF00296120 Electron-dense lipidic capillary deposits in Rett syndrome [Elektronische Daten] [R. Dieler, J. Schröder, K. Reddemann] Summary: Conjunctival, muscle, and peripheral artery biopsies were examined by light and electron microscopy in a patient with clinically diagnosed Rett syndrome. In capillaries, amorphous and membranous electron-dense deposits were observed (a) endoluminally attached to endothelial cell membranes, (b) within junctional clefts of adjacent endothelial cells, and (c) at abluminal sites of endothelial cells. In addition, electron-dense deposits layiisolated or inside multivesicular bodies in endothelial cells and pericytes. These findings have not been reported before in Rett syndrome. They were not seen in agematched normal or pathological control cases and are suggested to indicate deposition of an as yet unknown lipidic plasma component possibly in association with impairment of the blood-tissue barrier. Springer-Verlag, 1990 Rett syndrome nationallicence Mental retardation nationallicence Capillaries nationallicence Dieler R. Institut für Neuropathologie, Klinikum der Rheinisch-Westfälischen Technischen Hochschule, Pauwelsstrasse 30, D-5100, Aachen, Federal Republic of Germany aut Schröder J. Institut für Neuropathologie, Klinikum der Rheinisch-Westfälischen Technischen Hochschule, Pauwelsstrasse 30, D-5100, Aachen, Federal Republic of Germany aut Reddemann K. Kinderklinik, Klinikum der Rheinisch-Westfälischen Technischen Hochschule, Pauwelsstrasse 30, D-5100, Aachen, Federal Republic of Germany aut Acta Neuropathologica Springer-Verlag 79/5(1990-02-01), 573-578 0001-6322 79:5<573 1990 79 401 https://doi.org/10.1007/BF00296120 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00296120 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Dieler R. Institut für Neuropathologie, Klinikum der Rheinisch-Westfälischen Technischen Hochschule, Pauwelsstrasse 30, D-5100, Aachen, Federal Republic of Germany aut NATIONALLICENCE 700 1- Schröder J. Institut für Neuropathologie, Klinikum der Rheinisch-Westfälischen Technischen Hochschule, Pauwelsstrasse 30, D-5100, Aachen, Federal Republic of Germany aut NATIONALLICENCE 700 1- Reddemann K. Kinderklinik, Klinikum der Rheinisch-Westfälischen Technischen Hochschule, Pauwelsstrasse 30, D-5100, Aachen, Federal Republic of Germany aut NATIONALLICENCE 773 0- Acta Neuropathologica Springer-Verlag 79/5(1990-02-01), 573-578 0001-6322 79:5<573 1990 79 401 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer