caa a22 4500 465767753 CHVBK 20180323111919.0 cr unu---uuuuu 170327e19901001xx s 000 0 eng 10.1007/BF00307627 doi (NATIONALLICENCE)springer-10.1007/BF00307627 Adrenergic innervation of blood vessels in rat tibial nerve during Wallerian degeneration [Elektronische Daten] [J. Koistinaho, K. Wadhwani, C. Latker, A. Balbo, S. Rapoport] Summary: Adrenergic innervation of blood vessels in rat tibial nerve during Wallerian degeneration was examined, using the formaldehyde-induced histo-fluorescence method. The left sciatic nerve was transected at the level of the sciatic notch, whereas the right sciatic nerve was left intact and used as control. At 1, 3, 7, 14, 42, 56 or 84 days after transection, the tibial nerves of the transected and contralateral sides were exposed. Pieces of each nerve were used for light microscopy or for examination of adrenergic innervation with the fluorescence microscope. One day after transection, no adrenergic nerve fiber was observed in the endoneurium of the transected nerve. After 3 days, adrenergic innervation of small-and medium-sized arterioles in the epi-perineurium was absent, and after 7 days no fibers were visible around large arterioles. Fluorescent fibers were not detected even at 84 days post-surgery. It is concluded that adrenergic innervation of blood vessels in the rat tibial nerve is irreversibly lost after permanent axotomy, and that adrenergic regulation of nerve blood flow may also be lost. Springer-Verlag, 1990 Tibial nerve nationallicence Blood vessel nationallicence Wallerian degeneration nationallicence Adrenergic innervation nationallicence Blood flow regulation nationallicence Koistinaho J. Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Bldg 10, Rm 6C103, 20892, Bethesda, MD, USA aut Wadhwani K. Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Bldg 10, Rm 6C103, 20892, Bethesda, MD, USA aut Latker C. Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Bldg 10, Rm 6C103, 20892, Bethesda, MD, USA aut Balbo A. Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Bldg 10, Rm 6C103, 20892, Bethesda, MD, USA aut Rapoport S. Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Bldg 10, Rm 6C103, 20892, Bethesda, MD, USA aut Acta Neuropathologica Springer-Verlag 80/6(1990-10-01), 604-610 0001-6322 80:6<604 1990 80 401 https://doi.org/10.1007/BF00307627 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00307627 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Koistinaho J. Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Bldg 10, Rm 6C103, 20892, Bethesda, MD, USA aut NATIONALLICENCE 700 1- Wadhwani K. Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Bldg 10, Rm 6C103, 20892, Bethesda, MD, USA aut NATIONALLICENCE 700 1- Latker C. Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Bldg 10, Rm 6C103, 20892, Bethesda, MD, USA aut NATIONALLICENCE 700 1- Balbo A. Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Bldg 10, Rm 6C103, 20892, Bethesda, MD, USA aut NATIONALLICENCE 700 1- Rapoport S. Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Bldg 10, Rm 6C103, 20892, Bethesda, MD, USA aut NATIONALLICENCE 773 0- Acta Neuropathologica Springer-Verlag 80/6(1990-10-01), 604-610 0001-6322 80:6<604 1990 80 401 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer