caa a22 4500 465768148 CHVBK 20180323111920.0 cr unu---uuuuu 170327e19900801xx s 000 0 eng 10.1007/BF00307696 doi (NATIONALLICENCE)springer-10.1007/BF00307696 Anti-macrophage CR3 antibody blocks myelin phagocytosis by macrophages in vitro [Elektronische Daten] [W. Brück, R. Friede] Summary: Myelin phagocytosis in Wallerian degeneration of peripheral nerves depends on invasion of nerves by non-resident macrophages. The present study was done to clarify the role of the macrophage complement receptor type 3 (CR3) in myelin removal. Myelin phagocytic capacity of invading macrophages was abolished by treatment of cultured nerves and macrophages with anti-CR3 antibody or by serum complement depletion with cobra venom factor. This indicates that myelin phagocytosis is mediated by the macrophage CR3. Springer-Verlag, 1990 Myelin phagocytosis nationallicence Macrophages nationallicence Complement receptor type 3 nationallicence Organ culture nationallicence Brück W. Abteilung für Neuropathologie, Universität Göttingen, Robert-Koch-Strasse 40, D-3400, Göttingen, Federal Republic of Germany aut Friede R. Abteilung für Neuropathologie, Universität Göttingen, Robert-Koch-Strasse 40, D-3400, Göttingen, Federal Republic of Germany aut Acta Neuropathologica Springer-Verlag 80/4(1990-08-01), 415-418 0001-6322 80:4<415 1990 80 401 https://doi.org/10.1007/BF00307696 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00307696 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Brück W. Abteilung für Neuropathologie, Universität Göttingen, Robert-Koch-Strasse 40, D-3400, Göttingen, Federal Republic of Germany aut NATIONALLICENCE 700 1- Friede R. Abteilung für Neuropathologie, Universität Göttingen, Robert-Koch-Strasse 40, D-3400, Göttingen, Federal Republic of Germany aut NATIONALLICENCE 773 0- Acta Neuropathologica Springer-Verlag 80/4(1990-08-01), 415-418 0001-6322 80:4<415 1990 80 401 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer