caa a22 4500 465768555 CHVBK 20180323111922.0 cr unu---uuuuu 170327e19900601xx s 000 0 eng 10.1007/BF00308929 doi (NATIONALLICENCE)springer-10.1007/BF00308929 Axonal swellings in the corticospinal tracts in amyotrophic lateral sclerosis [Elektronische Daten] [K. Okamoto, S. Hirai, M. Shoji, Y. Senoh, T. Yamazaki] Summary: In 2 of 16 cases with sporadic amyotrophic lateral sclerosis (ALS) large numbers of axonal swellings were observed in the corticospinal tracts over a region extending from the posterior limbs of internal capsules to the bulbar pyramids. On electron microscopy, these axonal swellings were seen to consist of accumulations of neurofilaments and altered neuronal organelles (mitochondria and secondary lysosomes). Their morphology differed from the spheroids seen in the anterior horn in ALS. Springer-Verlag, 1990 Amyotrophic lateral sclerosis nationallicence Spheroid nationallicence Corticospinal tract nationallicence Okamoto K. Institute of Neurology and Rehabilitation, Gunma University, 3-39-22, Showa-machi, 371, Maebashi, Gunma, Japan aut Hirai S. Institute of Neurology and Rehabilitation, Gunma University, 3-39-22, Showa-machi, 371, Maebashi, Gunma, Japan aut Shoji M. Institute of Neurology and Rehabilitation, Gunma University, 3-39-22, Showa-machi, 371, Maebashi, Gunma, Japan aut Senoh Y. Institute of Neurology and Rehabilitation, Gunma University, 3-39-22, Showa-machi, 371, Maebashi, Gunma, Japan aut Yamazaki T. Institute of Neurology and Rehabilitation, Gunma University, 3-39-22, Showa-machi, 371, Maebashi, Gunma, Japan aut Acta Neuropathologica Springer-Verlag 80/2(1990-06-01), 222-226 0001-6322 80:2<222 1990 80 401 https://doi.org/10.1007/BF00308929 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00308929 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Okamoto K. Institute of Neurology and Rehabilitation, Gunma University, 3-39-22, Showa-machi, 371, Maebashi, Gunma, Japan aut NATIONALLICENCE 700 1- Hirai S. Institute of Neurology and Rehabilitation, Gunma University, 3-39-22, Showa-machi, 371, Maebashi, Gunma, Japan aut NATIONALLICENCE 700 1- Shoji M. Institute of Neurology and Rehabilitation, Gunma University, 3-39-22, Showa-machi, 371, Maebashi, Gunma, Japan aut NATIONALLICENCE 700 1- Senoh Y. Institute of Neurology and Rehabilitation, Gunma University, 3-39-22, Showa-machi, 371, Maebashi, Gunma, Japan aut NATIONALLICENCE 700 1- Yamazaki T. Institute of Neurology and Rehabilitation, Gunma University, 3-39-22, Showa-machi, 371, Maebashi, Gunma, Japan aut NATIONALLICENCE 773 0- Acta Neuropathologica Springer-Verlag 80/2(1990-06-01), 222-226 0001-6322 80:2<222 1990 80 401 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer