caa a22 4500 46576875X CHVBK 20180323111923.0 cr unu---uuuuu 170327e19901201xx s 000 0 eng 10.1007/BF00334514 doi (NATIONALLICENCE)springer-10.1007/BF00334514 Polar spongioblastoma: an immunohistochemical and electron microscopical study [Elektronische Daten] [G. Jansen, D. Troost, K. Dingemans] Summary: A case is reported of a 9-year-old boy with a cerebral polar spongioblastoma. This neoplasm, first described by Russell and Cairns in 1947, is morphologically a distinct entity characterized by bipolar tumor cells with palisading nuclei. In the case under study immunoreactivity for neuron-specific enolase was found and ultrastructural features of developing neuronal elements were present. A neuro-endocrine nature was suggested by de Chadarévian et al. (1984) in a morphologically similar case. These findings are in contrast with the longheld view that the polar spongioblastoma is cytogenetically related to the embryonal radial glial cells. Springer-Verlag, 1990 Cerebral tumor nationallicence Polar spongioblastoma nationallicence Astrocytoma nationallicence Immunohistochemistry nationallicence Electron microscopy nationallicence Jansen G. Department of Pathology, Subdivision of Neuropathology, University Hospital Utrecht, P.O. Box 85500, NI-3508 GA, Utrecht, The Netherlands aut Troost D. Department of Pathology, Subdivision of Neuropathology, Academic Medical Center, Amsterdam, The Netherlands aut Dingemans K. Subdivision of Electron Microscopy, Academic Medical Center, Amsterdam, The Netherlands aut Acta Neuropathologica Springer-Verlag 81/2(1990-12-01), 228-232 0001-6322 81:2<228 1990 81 401 https://doi.org/10.1007/BF00334514 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00334514 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Jansen G. Department of Pathology, Subdivision of Neuropathology, University Hospital Utrecht, P.O. Box 85500, NI-3508 GA, Utrecht, The Netherlands aut NATIONALLICENCE 700 1- Troost D. Department of Pathology, Subdivision of Neuropathology, Academic Medical Center, Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- Dingemans K. Subdivision of Electron Microscopy, Academic Medical Center, Amsterdam, The Netherlands aut NATIONALLICENCE 773 0- Acta Neuropathologica Springer-Verlag 81/2(1990-12-01), 228-232 0001-6322 81:2<228 1990 81 401 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer