caa a22 4500 465768830 CHVBK 20180323111923.0 cr unu---uuuuu 170327e19901201xx s 000 0 eng 10.1007/BF00334512 doi (NATIONALLICENCE)springer-10.1007/BF00334512 An autopsy case of human T lymphotropic virus type I-associated myelopathy (HAM) with a duration of 28 years [Elektronische Daten] [S. Sasaki, T. Komori, S. Maruyama, M. Takeishi, Y Iwasaki] Summary: An autopsy case of human T lymphotropic virus I-associated myelopathy (HAM) of a duration of 28 years in a 61-year-old man with serological confirmation of HTLV-I infection was reported. The spinal cord was grossly atrophic. There was severe symmetrical degeneration of the lateral funiculi, particularly of the bilateral pyramidal tracts, involving all levels of the spinal cord, but anterior horn cells were relatively well preserved. In the most severely damaged middle and lower thoracic segments, the white matter degeneration also involved the anterior funiculi. In the degenerated white matter, both the myelin and axons were equally lost and had been replaced by glial scars. Marked adventitial fibrosis was commonly seen in small parenchymal vessls in both the white and gray matter. Although there was no evidence of inflammation in the spinal cord, mild lymphocytic infiltration was occasionally observed in the subarachnoid and perivascular spaces in the brain stem, cerebellum and cerebrum. This case was considered as a burnt-out case of HAM. Springer-Verlag, 1990 HTLV-I nationallicence Tropical spastic paraparesis nationallicence Chronic progressive myelopathy nationallicence Sasaki S. Department of Neurology, Neurological Institute, Tokyo Women's Medical College, 8-1 Kawada-cho, Shiniuku-ku, 162, Tokyo, Japan aut Komori T. Department of Neurology, Neurological Institute, Tokyo Women's Medical College, 8-1 Kawada-cho, Shiniuku-ku, 162, Tokyo, Japan aut Maruyama S. Department of Neurology, Neurological Institute, Tokyo Women's Medical College, 8-1 Kawada-cho, Shiniuku-ku, 162, Tokyo, Japan aut Takeishi M. Department of Pathology, Tokyo Women's Medical College, 8-1 Kawada-cho, Shiniuku-ku, 162, Tokyo, Japan aut Iwasaki Y. Department of Neurological Sciences, Tohoku University School of Medicine, 1-1 Seiryo-Machi, 980, Sendai, Japan aut Acta Neuropathologica Springer-Verlag 81/2(1990-12-01), 219-222 0001-6322 81:2<219 1990 81 401 https://doi.org/10.1007/BF00334512 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00334512 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sasaki S. Department of Neurology, Neurological Institute, Tokyo Women's Medical College, 8-1 Kawada-cho, Shiniuku-ku, 162, Tokyo, Japan aut NATIONALLICENCE 700 1- Komori T. Department of Neurology, Neurological Institute, Tokyo Women's Medical College, 8-1 Kawada-cho, Shiniuku-ku, 162, Tokyo, Japan aut NATIONALLICENCE 700 1- Maruyama S. Department of Neurology, Neurological Institute, Tokyo Women's Medical College, 8-1 Kawada-cho, Shiniuku-ku, 162, Tokyo, Japan aut NATIONALLICENCE 700 1- Takeishi M. Department of Pathology, Tokyo Women's Medical College, 8-1 Kawada-cho, Shiniuku-ku, 162, Tokyo, Japan aut NATIONALLICENCE 700 1- Iwasaki Y. Department of Neurological Sciences, Tohoku University School of Medicine, 1-1 Seiryo-Machi, 980, Sendai, Japan aut NATIONALLICENCE 773 0- Acta Neuropathologica Springer-Verlag 81/2(1990-12-01), 219-222 0001-6322 81:2<219 1990 81 401 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer