caa a22 4500 46576911X CHVBK 20180323111924.0 cr unu---uuuuu 170327e19900301xx s 000 0 eng 10.1007/BF00155547 doi (NATIONALLICENCE)springer-10.1007/BF00155547 Persistence of leptospiral agglutinins in Trinidadian survey subjects [Elektronische Daten] [C. Everard, S. Bennett] Participants in a survey for leptospiral agglutinating antibodies undertaken in Trinidad, West Indies, in 1977-78, were further monitored for up to 5-and-a-half years. 52 individuals with a titre ≥ 1:400 were matched for age, sex and occupation with seronegative subjects. They were re-bled twice (on average 2.38 and 4.84 years later), and changes of titre were noted. At the first follow-up, 78% of negative controls remained negative, and 22%, showed titre changes. Among the seropositive subjects, 47% showed a fall in titre, 38% showed no change, and in 15% the titre rose. New exposure rates between the original and first follow-up samples were 96/1,000 survey population per year in the controls, and 68/1,000 for the subjects with titres > 1:400. Between the first and second followup, 47% of the seropositive subjects lost titre, 40% showed no change, and 13% showed a rise in titre. These data demonstrate that although antibody titres may be maintained for a few years at the same level, or show a loss as is usually expected, about 8.3% of individuals in Trinidad may be infected/reinfected per year. The infection/reinfection rate is an important factor in the epidemiology of leptospirosis. Kluwer Academic Publishers, 1990 Leptospires nationallicence Antibody persistence nationallicence West Indies nationallicence Everard C. Leptospira Laboratory, Enmore 2, Lower Collymore Rock, St. Michael, Barbados, England aut Bennett S. Tropical Epidemiology Unit, London School of Hygiene and Tropical Medicine, WC1E 7HT, London, England aut European Journal of Epidemiology Kluwer Academic Publishers 6/1(1990-03-01), 40-44 0393-2990 6:1<40 1990 6 10654 https://doi.org/10.1007/BF00155547 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00155547 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Everard C. Leptospira Laboratory, Enmore 2, Lower Collymore Rock, St. Michael, Barbados, England aut NATIONALLICENCE 700 1- Bennett S. Tropical Epidemiology Unit, London School of Hygiene and Tropical Medicine, WC1E 7HT, London, England aut NATIONALLICENCE 773 0- European Journal of Epidemiology Kluwer Academic Publishers 6/1(1990-03-01), 40-44 0393-2990 6:1<40 1990 6 10654 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer