caa a22 4500 465769152 CHVBK 20180323111924.0 cr unu---uuuuu 170327e19900901xx s 000 0 eng 10.1007/BF00150434 doi (NATIONALLICENCE)springer-10.1007/BF00150434 Circulation in Italy of β-lactamase-producing strains within the major groups of bacterial pathogens [Elektronische Daten] [P. Varaldo, G. Nicoletti, G. Schito, A. Maida, B. Facinelli, S. Stefani, G. Gianrossi, E. Muresu] A multicenter study was undertaken in Italy to assess the circulation of β-lactamase-producing organisms and their current incidence within the major groups of bacterial pathogens. Almost four thousand strains, all freshly isolated from clinical material, were examined at four centers serving different areas of Italy. Despite some significant center-to-center differences, this survey documented the occurrence of a large overall circulation of β-lactamase-producing organisms among clinical bacterial isolates. In particular, ampicillin resistance was recorded in one third to one half of the isolates of some Enterobacteriaceae, including Escherichia coli, Proteus, and Citrobacter species, and 80-90% of these resistant strains proved to be B-lactamase producers. Both ampicillin resistance and β-lactamase production were almost the rule in other Enterobacteriaceae, including Klebsiella, Enterobacter, and Serratia species. β-lactamase was also produced by about 80% of glucose-non-fermenting gram-negative bacteria and Aeromonas hydrophila strains, by all of the isolates of Branhamella catarrhalis manifesting ampicillin resistance (i.e. more than half the total number of isolates), and by about two thirds of the ampicillin-resistantffaemophilus strains (which accounted for 20-25% of all Haemophilus isolates examined). In contrast, no B-lactamase producers were observed among Neisseria gonorrhoeae isolates. Kluwer Academic Publishers, 1990 β-Lactamase production nationallicence Antibiotic resistance nationallicence Bacterial pathogens nationallicence Varaldo P. Institute of Microbiology, University of Ancona Medical School - Via Ranieri, Monte d Ago, 60131, Ancona, Italy aut Nicoletti G. Institute of Microbiology, University of Catania, Italy aut Schito G. Institute of Microbiology, University of Genoa, Italy aut Maida A. Institute of Hygiene, University of Sassari, Italy aut Facinelli B. Institute of Microbiology, University of Ancona Medical School - Via Ranieri, Monte d Ago, 60131, Ancona, Italy aut Stefani S. Institute of Microbiology, University of Catania, Italy aut Gianrossi G. Institute of Microbiology, University of Genoa, Italy aut Muresu E. Institute of Hygiene, University of Sassari, Italy aut European Journal of Epidemiology Kluwer Academic Publishers 6/3(1990-09-01), 287-292 0393-2990 6:3<287 1990 6 10654 https://doi.org/10.1007/BF00150434 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00150434 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Varaldo P. Institute of Microbiology, University of Ancona Medical School - Via Ranieri, Monte d Ago, 60131, Ancona, Italy aut NATIONALLICENCE 700 1- Nicoletti G. Institute of Microbiology, University of Catania, Italy aut NATIONALLICENCE 700 1- Schito G. Institute of Microbiology, University of Genoa, Italy aut NATIONALLICENCE 700 1- Maida A. Institute of Hygiene, University of Sassari, Italy aut NATIONALLICENCE 700 1- Facinelli B. Institute of Microbiology, University of Ancona Medical School - Via Ranieri, Monte d Ago, 60131, Ancona, Italy aut NATIONALLICENCE 700 1- Stefani S. Institute of Microbiology, University of Catania, Italy aut NATIONALLICENCE 700 1- Gianrossi G. Institute of Microbiology, University of Genoa, Italy aut NATIONALLICENCE 700 1- Muresu E. Institute of Hygiene, University of Sassari, Italy aut NATIONALLICENCE 773 0- European Journal of Epidemiology Kluwer Academic Publishers 6/3(1990-09-01), 287-292 0393-2990 6:3<287 1990 6 10654 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer