caa a22 4500 465769195 CHVBK 20180323111924.0 cr unu---uuuuu 170327e19900901xx s 000 0 eng 10.1007/BF00150442 doi (NATIONALLICENCE)springer-10.1007/BF00150442 Antibodies to hepatitis C virus in blood donors [Elektronische Daten] [P. Ferroni, A. Tagger, M. Ribero, A. Grossi, F. Pregliasco, M. Pasquali, S. Salvaneschi] Recently a recombinant polypeptide of hepatitis C virus (HCV) has been developed by the Chiron Corporation in California. This antigen has been used to develop an ELISA test (Ortho Diagnostic Systems) for serum anti-HCV antibodies. Preliminary data have shown that this virus is the major cause of NANB hepatitis in the world. We examined differences in anti-HCV prevalence among subgroups of blood donors (total sera examined 639) classified for past or present exposure to HBV or not, and for ALT levels. The anti-HCV prevalence found in regular blood donors with normal ALT levels and no antibody to HBcAg was 1.2%. No significant difference in the anti-HCV prevalence was found among other subgroups of blood donors except that a higher prevalence (10%) was found in a group with both elevated ALT and HBV markers. These preliminary findings suggest that the policy of blood supply should take into account the advent of HCV antibody test. Kluwer Academic Publishers, 1990 Hepatitis C virus nationallicence Hepatitis B virus nationallicence Antibody nationallicence Blood donors nationallicence Ferroni P. Istituto di Virologia, Università di Milano, Via C. Pascal, 38, 20123, Milano, Italy aut Tagger A. Istituto di Virologia, Università di Milano, Via C. Pascal, 38, 20123, Milano, Italy aut Ribero M. Istituto di Igiene, Universita di Milano, Italy aut Grossi A. Istituto di Virologia, Università di Milano, Via C. Pascal, 38, 20123, Milano, Italy aut Pregliasco F. Istituto di Virologia, Università di Milano, Via C. Pascal, 38, 20123, Milano, Italy aut Pasquali M. Servizio di Immunoematologia, Istituto Nazionale dei Tumori, Milano, Italy aut Salvaneschi S. Centro Trasfusionale A. V.I.S., Pavia, Italy aut European Journal of Epidemiology Kluwer Academic Publishers 6/3(1990-09-01), 326-328 0393-2990 6:3<326 1990 6 10654 https://doi.org/10.1007/BF00150442 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00150442 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ferroni P. Istituto di Virologia, Università di Milano, Via C. Pascal, 38, 20123, Milano, Italy aut NATIONALLICENCE 700 1- Tagger A. Istituto di Virologia, Università di Milano, Via C. Pascal, 38, 20123, Milano, Italy aut NATIONALLICENCE 700 1- Ribero M. Istituto di Igiene, Universita di Milano, Italy aut NATIONALLICENCE 700 1- Grossi A. Istituto di Virologia, Università di Milano, Via C. Pascal, 38, 20123, Milano, Italy aut NATIONALLICENCE 700 1- Pregliasco F. Istituto di Virologia, Università di Milano, Via C. Pascal, 38, 20123, Milano, Italy aut NATIONALLICENCE 700 1- Pasquali M. Servizio di Immunoematologia, Istituto Nazionale dei Tumori, Milano, Italy aut NATIONALLICENCE 700 1- Salvaneschi S. Centro Trasfusionale A. V.I.S., Pavia, Italy aut NATIONALLICENCE 773 0- European Journal of Epidemiology Kluwer Academic Publishers 6/3(1990-09-01), 326-328 0393-2990 6:3<326 1990 6 10654 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer