caa a22 4500 465769349 CHVBK 20180323111924.0 cr unu---uuuuu 170327e19900901xx s 000 0 eng 10.1007/BF00150430 doi (NATIONALLICENCE)springer-10.1007/BF00150430 Dietary vitamin A, beta carotene and risk of epidermoid lung cancer in South-Western France [Elektronische Daten] [J. Dartigues, F. Dabis, N. Gros, A. Moise, G. Bois, R. Salamon, J. Dilhuydy, G. Courty] This hospital-based case-control study was designed to investigate the association of low dietary vitamin A and beta carotene consumption with epidermoid lung cancer. Cases were patients with histologically confirmed epidermoid lung cancer diagnosed in six selected hospitals of south-western France in 1983-84. Controls were selected from patients admitted to the same hospitals during the same period with diagnoses other than cancer. Cases and controls were matched for sex, age, place of residence, occupation, professional exposure to carcinogens, tobacco and alcohol consumption. A total of 106 cases of epidermoid lung cancer and 212 controls were interviewed on their typical weekly intake of 80 food items rich in preformed vitamin A and beta carotene. Index measures of the vitamin A and beta carotene daily intakes were computed for each individual patient and expressed in retinol equivalent (RE). A statistically significant odds ratio (OR) was found for preformed vitamin A (OR=4.3; 95% CI: 2.5-7.3) with the threshold of 1,000 RE. A similar result was found for beta carotene with the same threshold (OR = 4.1; 95% CI: 2.3-7.4). Using the conditional logistic regression, consumption of preformed vitamin A and consumption of beta carotene were significantly and independently associated with epidermoid lung cancer. While confirming the protective role of beta carotene against epidermoid lung cancer, this study also shows that preformed vitamin A might have a distinct and important protective effect. Kluwer Academic Publishers, 1990 Lung cancer nationallicence Vitamin A nationallicence Beta carotene nationallicence Dartigues J. Laboratoire d Epidémiologie et Biostatistiques, Université Bordeaux II, 33076, Bordeaux Cedex, France aut Dabis F. Laboratoire d Epidémiologie et Biostatistiques, Université Bordeaux II, 33076, Bordeaux Cedex, France aut Gros N. Dispensaire de Pneumologie, Hôpital d'Angoulème, 16000, Angoulème, France aut Moise A. Laboratoire d Epidémiologie et Biostatistiques, Université Bordeaux II, 33076, Bordeaux Cedex, France aut Bois G. Dispensaire de Pneumologie, Hôpital d'Angoulème, 16000, Angoulème, France aut Salamon R. Laboratoire d Epidémiologie et Biostatistiques, Université Bordeaux II, 33076, Bordeaux Cedex, France aut Dilhuydy J. Service de Radiothérapie, Fondation Bergonié, 33000, Bordeaux, France aut Courty G. aut European Journal of Epidemiology Kluwer Academic Publishers 6/3(1990-09-01), 261-265 0393-2990 6:3<261 1990 6 10654 https://doi.org/10.1007/BF00150430 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00150430 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Dartigues J. Laboratoire d Epidémiologie et Biostatistiques, Université Bordeaux II, 33076, Bordeaux Cedex, France aut NATIONALLICENCE 700 1- Dabis F. Laboratoire d Epidémiologie et Biostatistiques, Université Bordeaux II, 33076, Bordeaux Cedex, France aut NATIONALLICENCE 700 1- Gros N. Dispensaire de Pneumologie, Hôpital d'Angoulème, 16000, Angoulème, France aut NATIONALLICENCE 700 1- Moise A. Laboratoire d Epidémiologie et Biostatistiques, Université Bordeaux II, 33076, Bordeaux Cedex, France aut NATIONALLICENCE 700 1- Bois G. Dispensaire de Pneumologie, Hôpital d'Angoulème, 16000, Angoulème, France aut NATIONALLICENCE 700 1- Salamon R. Laboratoire d Epidémiologie et Biostatistiques, Université Bordeaux II, 33076, Bordeaux Cedex, France aut NATIONALLICENCE 700 1- Dilhuydy J. Service de Radiothérapie, Fondation Bergonié, 33000, Bordeaux, France aut NATIONALLICENCE 700 1- Courty G. aut NATIONALLICENCE 773 0- European Journal of Epidemiology Kluwer Academic Publishers 6/3(1990-09-01), 261-265 0393-2990 6:3<261 1990 6 10654 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer