caa a22 4500 465769780 CHVBK 20180323111926.0 cr unu---uuuuu 170327e19900601xx s 000 0 eng 10.1007/BF00145788 doi (NATIONALLICENCE)springer-10.1007/BF00145788 An outbreak of hepatitis a in young adults in central Italy [Elektronische Daten] [T. Stroffolini, W. Biagini, L. Lorenzoni, G. Palazzesi, M. Divizia, R. Frongillo] Between September, 1988 and January, 1989 a common source outbreak of 47 cases of serologically confirmed hepatitis A occurred in a town of central Italy. Thirty-eight cases were primary, three co-primary and six secondary. The highest age-specific attack rate was seen in subjects aged 15-24 years (120 per 100,000); the mean age of cases was 24.6 years and the median age was 22 years. A matched triplet case-control study showed significant association between the disease and consumption of either raw mussels (41% of cases, compared with 10% of controls; P < 0.0001) or a single brand of mineral water (63% of cases, compared with 41% of controls; P < 0.05). The mean age of the cases reflects the shift in primary susceptibility to the infection from younger to older age groups, a finding which has recently been demonstrated by several seroepidemiological surveys in Italy. Gustav Fischer, 1990 Hepatitis A nationallicence Outbreak nationallicence Adults nationallicence Stroffolini T. Laboratorio di Epidemiologia, Istituto Superiore di Sanitá, Viale Regina Elena, 299, Roma, Italy aut Biagini W. Direzione Sanitaria, Ospedale di Term, Italy aut Lorenzoni L. Direzione Sanitaria, Ospedale di Term, Italy aut Palazzesi G. Servizio di Immunoematologia, Ospedale di Term, Italy aut Divizia M. Istituto d'Igiene e Medicina Preventiva, II Universitá di Roma, Italy aut Frongillo R. Clinica Malattie Infettive dell'Universitá di Perugia, sede di Term, Italy aut European Journal of Epidemiology Kluwer Academic Publishers 6/2(1990-06-01), 156-159 0393-2990 6:2<156 1990 6 10654 https://doi.org/10.1007/BF00145788 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00145788 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Stroffolini T. Laboratorio di Epidemiologia, Istituto Superiore di Sanitá, Viale Regina Elena, 299, Roma, Italy aut NATIONALLICENCE 700 1- Biagini W. Direzione Sanitaria, Ospedale di Term, Italy aut NATIONALLICENCE 700 1- Lorenzoni L. Direzione Sanitaria, Ospedale di Term, Italy aut NATIONALLICENCE 700 1- Palazzesi G. Servizio di Immunoematologia, Ospedale di Term, Italy aut NATIONALLICENCE 700 1- Divizia M. Istituto d'Igiene e Medicina Preventiva, II Universitá di Roma, Italy aut NATIONALLICENCE 700 1- Frongillo R. Clinica Malattie Infettive dell'Universitá di Perugia, sede di Term, Italy aut NATIONALLICENCE 773 0- European Journal of Epidemiology Kluwer Academic Publishers 6/2(1990-06-01), 156-159 0393-2990 6:2<156 1990 6 10654 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer