caa a22 4500 465772382 CHVBK 20180323111932.0 cr unu---uuuuu 170327e19900601xx s 000 0 eng 10.1007/BF00169668 doi (NATIONALLICENCE)springer-10.1007/BF00169668 Sclerosing therapy with bleomycin emulsion for lymphangioma in children [Elektronische Daten] [Koichi Tanaka, Yukihiro Inomata, Hirofumi Utsunomiya, Shinji Uemoto, Katsuhiro Asonuma, Tetsuo Katayama, Kazue Ozawa, M. Hashida] Forty-seven children with lymphangioma were treated by sclerosing therapy with bleomycin (BLM) emulsion between may 1976 and March 1988. Injection of 0.3 to 0.6 mg/kg body weight BLM emulsion into the cavity was repeated at intervals of 4 to 6 weeks. The lymphangioma regressed in 41 (87%) and almost disappeared in 20 (43%). The response was greater when the lymphangioma was cystic rather than cavernous. In the cases that responded, the total injected dose was 0.6 to 4 mg/kg. This therapy proved to be dangerous for large cervicomediastinal lymphangiomas in young infants because the cystic mass enlarged transiently after local injection and airway compression resulted. Pulmonary fibrosis was not observed. There was no recurrence of the residual induration after BLM emulsion therapy. Antenatal ultrasonography and magnetic resonance imaging have been shown to be useful diagnostic aids. Springer-Verlag, 1990 Cystic hygroma nationallicence Lymphangioma nationallicence Sclerosing therapy nationallicence Bleomycin nationallicence Tanaka Koichi Second Department of Surgery, Kyoto University School of Medicine, 54 Kawara-cho, Shogoin, 606, Sakyo-ku Kyoto, Japan aut Inomata Yukihiro Second Department of Surgery, Kyoto University School of Medicine, 54 Kawara-cho, Shogoin, 606, Sakyo-ku Kyoto, Japan aut Utsunomiya Hirofumi Second Department of Surgery, Kyoto University School of Medicine, 54 Kawara-cho, Shogoin, 606, Sakyo-ku Kyoto, Japan aut Uemoto Shinji Second Department of Surgery, Kyoto University School of Medicine, 54 Kawara-cho, Shogoin, 606, Sakyo-ku Kyoto, Japan aut Asonuma Katsuhiro Second Department of Surgery, Kyoto University School of Medicine, 54 Kawara-cho, Shogoin, 606, Sakyo-ku Kyoto, Japan aut Katayama Tetsuo Second Department of Surgery, Kyoto University School of Medicine, 54 Kawara-cho, Shogoin, 606, Sakyo-ku Kyoto, Japan aut Ozawa Kazue Second Department of Surgery, Kyoto University School of Medicine, 54 Kawara-cho, Shogoin, 606, Sakyo-ku Kyoto, Japan aut Hashida M. Faculty of Pharmaceutical Science, Kyoto University, 54 Kawara-cho, Shogoin, 606, Sakyo-ku Kyoto, Japan aut Pediatric Surgery International Springer-Verlag 5/4(1990-06-01), 270-273 0179-0358 5:4<270 1990 5 383 https://doi.org/10.1007/BF00169668 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00169668 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Tanaka Koichi Second Department of Surgery, Kyoto University School of Medicine, 54 Kawara-cho, Shogoin, 606, Sakyo-ku Kyoto, Japan aut NATIONALLICENCE 700 1- Inomata Yukihiro Second Department of Surgery, Kyoto University School of Medicine, 54 Kawara-cho, Shogoin, 606, Sakyo-ku Kyoto, Japan aut NATIONALLICENCE 700 1- Utsunomiya Hirofumi Second Department of Surgery, Kyoto University School of Medicine, 54 Kawara-cho, Shogoin, 606, Sakyo-ku Kyoto, Japan aut NATIONALLICENCE 700 1- Uemoto Shinji Second Department of Surgery, Kyoto University School of Medicine, 54 Kawara-cho, Shogoin, 606, Sakyo-ku Kyoto, Japan aut NATIONALLICENCE 700 1- Asonuma Katsuhiro Second Department of Surgery, Kyoto University School of Medicine, 54 Kawara-cho, Shogoin, 606, Sakyo-ku Kyoto, Japan aut NATIONALLICENCE 700 1- Katayama Tetsuo Second Department of Surgery, Kyoto University School of Medicine, 54 Kawara-cho, Shogoin, 606, Sakyo-ku Kyoto, Japan aut NATIONALLICENCE 700 1- Ozawa Kazue Second Department of Surgery, Kyoto University School of Medicine, 54 Kawara-cho, Shogoin, 606, Sakyo-ku Kyoto, Japan aut NATIONALLICENCE 700 1- Hashida M. Faculty of Pharmaceutical Science, Kyoto University, 54 Kawara-cho, Shogoin, 606, Sakyo-ku Kyoto, Japan aut NATIONALLICENCE 773 0- Pediatric Surgery International Springer-Verlag 5/4(1990-06-01), 270-273 0179-0358 5:4<270 1990 5 383 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer