caa a22 4500 465772668 CHVBK 20180323111933.0 cr unu---uuuuu 170327e19900201xx s 000 0 eng 10.1007/BF00178229 doi (NATIONALLICENCE)springer-10.1007/BF00178229 Cholelithiasis in thalassemic children [Elektronische Daten] [Soottiporn Chittmittrapap, Vacharee Buachum, Ayut Dharmklong-at] A prospective, case-controlled study was performed in 49 thalassemic children with severe hemolysis using real-time ultrasonographic (US) examination of the gallbladder and biliary system to detect gallstones, Seven children showed the presence of gallstones; 3 had undergone splenectomy before this study. Gallstones were found in 3 patients while admitted for elective splenectomy. The 14.3% incidence of gallstones in this group was significantly higher than in the control group. The children with gallstones also had significantly higher mean serum bilirubin levels, but their mean hemoglobin levels and mean intervals of blood transfusion were not significantly different from those thalassemic children with severe hemolysis who did not have gallstones. The proportion of gallstones also increased with age. US examination of the biliary tract is a simple, noninvasive technique and is practicable in children. This study indicates the need to screen for gallstones in high-risk groups of thalassemic children. Early detection of gallstones leads to correct management and better outcome, especially in splenectomized patients, who are more susceptible to infection. Springer-Verlag, 1990 Gallstones nationallicence Cholelithiasis nationallicence Thalassemia nationallicence Chronic hemolysis nationallicence Chittmittrapap Soottiporn Division of Paediatric Surgery, Department of Surgery, Chulalongkorn University Hospital, 10500, Patumwan, Bangkok, Thailand aut Buachum Vacharee Department of Radiology, Chulalongkorn University Hospital, 10500, Patumwan, Bangkok, Thailand aut Dharmklong-at Ayut Department of Paediatrics, Chulalongkorn University Hospital, 10500, Patumwan, Bangkok, Thailand aut Pediatric Surgery International Springer-Verlag 5/2(1990-02-01), 114-117 0179-0358 5:2<114 1990 5 383 https://doi.org/10.1007/BF00178229 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00178229 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Chittmittrapap Soottiporn Division of Paediatric Surgery, Department of Surgery, Chulalongkorn University Hospital, 10500, Patumwan, Bangkok, Thailand aut NATIONALLICENCE 700 1- Buachum Vacharee Department of Radiology, Chulalongkorn University Hospital, 10500, Patumwan, Bangkok, Thailand aut NATIONALLICENCE 700 1- Dharmklong-at Ayut Department of Paediatrics, Chulalongkorn University Hospital, 10500, Patumwan, Bangkok, Thailand aut NATIONALLICENCE 773 0- Pediatric Surgery International Springer-Verlag 5/2(1990-02-01), 114-117 0179-0358 5:2<114 1990 5 383 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer