caa a22 4500 465772730 CHVBK 20180323111933.0 cr unu---uuuuu 170327e19900201xx s 000 0 eng 10.1007/BF00178228 doi (NATIONALLICENCE)springer-10.1007/BF00178228 Immunohistochemical study of peptidergic nerves in infantile hypertrophic pyloric stenosis [Elektronische Daten] [Zhen-xin Shen, Ya-xiong She, Wan-chao Wang, Lin-hua Wang] In the recent literature it has been noted that peptidergic nerves may play an important role in infantile hypertrophic pyloric stenosis (HPS). Specimens from 20 patients with HPS were examined by immunohistochemistry with regard to the distribution of nerve cells and nerve fibers containing enkephalin (ENK), substance P (SP), and vasoactive intestinal polypeptide (VIP). Three subpopulations of peptides containing nerve cells and fibers were fairly numerous in the control specimens, but in the patients with HPS the density of the nerve fibers was markedly reduced and occasionally absent, especially the ENK- and VIP-containing fibers. In the myenteric plexus there was neither a reduction of nerve cell bodies nor of fibers. Our findings suggest that abnormalities of peptide-containing nerve fibers or impairment of neuronal function might results in HPS. Springer-Verlag, 1990 Infantile hypertrophic pyloric stenosis nationallicence Enkephalin nationallicence Substance P nationallicence Vasoactive intestinal polypeptide nationallicence Immunohistochemistry nationallicence Shen Zhen-xin Department of Pediatric Surgery, affiliated Xinhua Children's Hospital, Shanghai Second Medical University, Shanghai, Peoples Republic of China aut She Ya-xiong Department of Pediatric Surgery, affiliated Xinhua Children's Hospital, Shanghai Second Medical University, Shanghai, Peoples Republic of China aut Wang Wan-chao Department of Immunology, Shanghai Second Medical University, Shanghai, Peoples Republic of China aut Wang Lin-hua Department of Pediatric Surgery, affiliated Xinhua Children's Hospital, Shanghai Second Medical University, Shanghai, Peoples Republic of China aut Pediatric Surgery International Springer-Verlag 5/2(1990-02-01), 110-113 0179-0358 5:2<110 1990 5 383 https://doi.org/10.1007/BF00178228 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00178228 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Shen Zhen-xin Department of Pediatric Surgery, affiliated Xinhua Children's Hospital, Shanghai Second Medical University, Shanghai, Peoples Republic of China aut NATIONALLICENCE 700 1- She Ya-xiong Department of Pediatric Surgery, affiliated Xinhua Children's Hospital, Shanghai Second Medical University, Shanghai, Peoples Republic of China aut NATIONALLICENCE 700 1- Wang Wan-chao Department of Immunology, Shanghai Second Medical University, Shanghai, Peoples Republic of China aut NATIONALLICENCE 700 1- Wang Lin-hua Department of Pediatric Surgery, affiliated Xinhua Children's Hospital, Shanghai Second Medical University, Shanghai, Peoples Republic of China aut NATIONALLICENCE 773 0- Pediatric Surgery International Springer-Verlag 5/2(1990-02-01), 110-113 0179-0358 5:2<110 1990 5 383 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer