caa a22 4500 465773354 CHVBK 20180323111935.0 cr unu---uuuuu 170327e19900501xx s 000 0 eng 10.1007/BF00372618 doi (NATIONALLICENCE)springer-10.1007/BF00372618 Crystalline and amorphous gold in chrysiasis [Elektronische Daten] [H. Benn, B. von Gaudecker, M. Czank, H. Loeffler] Summary: Skin biopsy specimens from five patients (three females and two males) treated parenterally with gold were investigated using transmission electron microscopy. X-ray microanalysis and electron diffraction were used to determine the dermal heavy metal content. Additional sections were stained for light microscopic examination. The amount of elemental gold administered to the patients over a period of years to alleviate rheumatoid arthritis lay between a minimum of 4.0 g and a maximum of 10.0 g. In one and the same patient dermal histiocytic gold aggregations in sun-exposed areas of skin displayed a different pattern and divergent physiochemical states from the gold deposits in non-UV-exposed skin, where aurosome-like amorphous formations are found in the cells of the upper dermis. Additional spherical particles are associated predominantly with phagolysosomes in melanophages beneath solar-irradiated epidermis. Convergent beam electron diffraction proves the crystalline nature of the spherical auriferous deposits. The occurrence of skin rash was not related to different physicochemical states of the precious metal. Springer-Verlag, 1990 Chrysiasis nationallicence Gold nationallicence Melanophages nationallicence Crystal nationallicence Benn H. II. Medizinische Klinik und Poliklinik, Kiel, Federal Republic of Germany aut von Gaudecker B. Anatomisches Institut, Kiel, Federal Republic of Germany aut Czank M. Mineralogisch-Petrographisches Institut der UniversitÄt Kiel, Kiel, Federal Republic of Germany aut Loeffler H. II. Medizinische Klinik und Poliklinik, Kiel, Federal Republic of Germany aut Archives of Dermatological Research Springer-Verlag 282/3(1990-05-01), 172-178 0340-3696 282:3<172 1990 282 403 https://doi.org/10.1007/BF00372618 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00372618 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Benn H. II. Medizinische Klinik und Poliklinik, Kiel, Federal Republic of Germany aut NATIONALLICENCE 700 1- von Gaudecker B. Anatomisches Institut, Kiel, Federal Republic of Germany aut NATIONALLICENCE 700 1- Czank M. Mineralogisch-Petrographisches Institut der UniversitÄt Kiel, Kiel, Federal Republic of Germany aut NATIONALLICENCE 700 1- Loeffler H. II. Medizinische Klinik und Poliklinik, Kiel, Federal Republic of Germany aut NATIONALLICENCE 773 0- Archives of Dermatological Research Springer-Verlag 282/3(1990-05-01), 172-178 0340-3696 282:3<172 1990 282 403 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer