caa a22 4500 465773575 CHVBK 20180323111935.0 cr unu---uuuuu 170327e19900601xx s 000 0 eng 10.1007/BF00371638 doi (NATIONALLICENCE)springer-10.1007/BF00371638 Presence of Merkel cells in sun-exposed and not sun-exposed skin: a quantitative study [Elektronische Daten] [I. Moll, U. Bladt, E. Jung] Summary: Merkel cells (MCs), the neuroendocrine cells of the skin cannot be identified with certainty using conventional light microscopic staining methods. Using immunoperoxidase microscopy with antibodies specific for cytokeratin 18, which has been established as a marker protein of MCs, we have evaluated the numbers of MCs per mm2 skin in normal and sun-damaged upper arm skin. The sun-exposed skin contained twice as many MCs as the not sun exposed skin. Further quantification of MC density at various body sites (trunk, leg) showed a rather variable but often unexpectedly high MC density. The possible role of MC in development of actinic elastosis is discussed. Springer-Verlag, 1990 Merkel cells nationallicence Actinic skin damage nationallicence Cytokeratins nationallicence Moll I. Department of Dermatology, Mannheim Medical School, University of Heidelberg, P. O. Box 10 00 23, D-6800, Mannheim, Germany aut Bladt U. Department of Dermatology, Mannheim Medical School, University of Heidelberg, P. O. Box 10 00 23, D-6800, Mannheim, Germany aut Jung E. Department of Dermatology, Mannheim Medical School, University of Heidelberg, P. O. Box 10 00 23, D-6800, Mannheim, Germany aut Archives of Dermatological Research Springer-Verlag 282/4(1990-06-01), 213-216 0340-3696 282:4<213 1990 282 403 https://doi.org/10.1007/BF00371638 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00371638 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Moll I. Department of Dermatology, Mannheim Medical School, University of Heidelberg, P. O. Box 10 00 23, D-6800, Mannheim, Germany aut NATIONALLICENCE 700 1- Bladt U. Department of Dermatology, Mannheim Medical School, University of Heidelberg, P. O. Box 10 00 23, D-6800, Mannheim, Germany aut NATIONALLICENCE 700 1- Jung E. Department of Dermatology, Mannheim Medical School, University of Heidelberg, P. O. Box 10 00 23, D-6800, Mannheim, Germany aut NATIONALLICENCE 773 0- Archives of Dermatological Research Springer-Verlag 282/4(1990-06-01), 213-216 0340-3696 282:4<213 1990 282 403 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer