caa a22 4500 465773621 CHVBK 20180323111935.0 cr unu---uuuuu 170327e19900601xx s 000 0 eng 10.1007/BF00371645 doi (NATIONALLICENCE)springer-10.1007/BF00371645 Subpopulation of murine epidermal Langerhans cells identified by lectin-binding sites [Elektronische Daten] [K. Nakamura, A. Ishii, K. Tamaki] Summary: Lectin-binding profiles of epidermal Langerhans cells (LCs) were investigated in three strains of mice using immunofluorescence procedures. Three lectin-binding profiles were observed in each strain of mice. Most epidermal LCs reacted with concanavalin A (Con A) and Ricinus communis agglutinin 1 (RCA-1), whereas none reacted with Dolichos biflorus agglutinin (DBA). Peanut agglutinin (PNA) and wheat germ agglutinin (WGA) reacted with some of the epidermal LCs. These binding profiles were similar from site to site of the body in all strains of mice. We also investigated the lectin-binding profiles of epidermal Ia positive (Ia+) cells migrating into the grafted skin up to 165 days after transplantation. BALB/c (H-2d) murine skin was grafted onto the back of (C3H/He×BALB/c)F1 (H-2k×H-2d) mice. The percentages of migrating I-A+ epidermal cells reactive with PNA and WGA were different from those of the normal epidermis soon after grafting and reached a normal level at 43 days after grafting. Our results demonstrated that there is a heterogeneous population of epidermal LCs defined by lectin-binding profiles. Springer-Verlag, 1990 Langerhans cells nationallicence Ia antigen nationallicence Lectins nationallicence Subpopulation nationallicence Mouse nationallicence Nakamura K. Department of Dermatology, Faculty of Medicine, Tokyo University Branch Hospital, University of Tokyo, 3-28-6 Mejirodai, Bunkyo-ku, 112, Tokyo, Japan aut Ishii A. Department of Dermatology, Faculty of Medicine, Tokyo University Branch Hospital, University of Tokyo, 3-28-6 Mejirodai, Bunkyo-ku, 112, Tokyo, Japan aut Tamaki K. Department of Dermatology, Faculty of Medicine, Tokyo University Branch Hospital, University of Tokyo, 3-28-6 Mejirodai, Bunkyo-ku, 112, Tokyo, Japan aut Archives of Dermatological Research Springer-Verlag 282/4(1990-06-01), 253-257 0340-3696 282:4<253 1990 282 403 https://doi.org/10.1007/BF00371645 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00371645 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Nakamura K. Department of Dermatology, Faculty of Medicine, Tokyo University Branch Hospital, University of Tokyo, 3-28-6 Mejirodai, Bunkyo-ku, 112, Tokyo, Japan aut NATIONALLICENCE 700 1- Ishii A. Department of Dermatology, Faculty of Medicine, Tokyo University Branch Hospital, University of Tokyo, 3-28-6 Mejirodai, Bunkyo-ku, 112, Tokyo, Japan aut NATIONALLICENCE 700 1- Tamaki K. Department of Dermatology, Faculty of Medicine, Tokyo University Branch Hospital, University of Tokyo, 3-28-6 Mejirodai, Bunkyo-ku, 112, Tokyo, Japan aut NATIONALLICENCE 773 0- Archives of Dermatological Research Springer-Verlag 282/4(1990-06-01), 253-257 0340-3696 282:4<253 1990 282 403 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer