caa a22 4500 465773907 CHVBK 20180323111936.0 cr unu---uuuuu 170327e19900801xx s 000 0 eng 10.1007/BF00375720 doi (NATIONALLICENCE)springer-10.1007/BF00375720 Elastic properties of human skin: relation to age, sex, and anatomical region [Elektronische Daten] [A. Cua, K. Wilhelm, H. Maibach] Summary: Using a recently developed noninvasive, in vivo suction device for measuring skin elasticity, we evaluated age, sex, and regional differences in the viscoelastic properties of skin. A total of 33 volunteers participated in the study consisting of (a) 8 young females, (b) 9 old females, (c) 8 young males and (d) 8 old males. Measurements were performed on 11 anatomical regions; three different loads were applied: 100,200, and 500 mbar. The parameters used were: immediate distension (Ue); delayed distension (Uv); immediate retraction (Ur); and, final deformation (Uf). To compare between subjects and anatomical regions, relative parameters independent of skin thickness were calculated: Uv/Ue, the ratio between the viscoelastic properties of skin and immediate distension, and Ur/Uf, which measures the ability of the skin to regain its initial position after deformation. Generally, Uv/Ue increased while Ur/Uf decreased with aging. Responses were variable with respect to load applied. Variability within anatomical regions was also noted. However, differences between the sexes were not statistically significant for most regions. These findings are in congruence with earlier studies suggesting the differences are mainly attributable to alterations in the elastic fiber network. This procedure provides a simple, quantitative assessment of elastic properties of the skin. Its application may help in future investigations of other connective tissue disorders. Springer-Verlag, 1990 Elasticity nationallicence Aging nationallicence Suction nationallicence Cua A. Department of Dermatology, School of Medicine, University of California, San Francisco, CA, USA aut Wilhelm K. Department of Dermatology, School of Medicine, University of California, San Francisco, CA, USA aut Maibach H. Department of Dermatology, School of Medicine, University of California, San Francisco, CA, USA aut Archives of Dermatological Research Springer-Verlag 282/5(1990-08-01), 283-288 0340-3696 282:5<283 1990 282 403 https://doi.org/10.1007/BF00375720 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00375720 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Cua A. Department of Dermatology, School of Medicine, University of California, San Francisco, CA, USA aut NATIONALLICENCE 700 1- Wilhelm K. Department of Dermatology, School of Medicine, University of California, San Francisco, CA, USA aut NATIONALLICENCE 700 1- Maibach H. Department of Dermatology, School of Medicine, University of California, San Francisco, CA, USA aut NATIONALLICENCE 773 0- Archives of Dermatological Research Springer-Verlag 282/5(1990-08-01), 283-288 0340-3696 282:5<283 1990 282 403 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer