caa a22 4500 465773966 CHVBK 20180323111936.0 cr unu---uuuuu 170327e19900101xx s 000 0 eng 10.1007/BF00493465 doi (NATIONALLICENCE)springer-10.1007/BF00493465 Macrophage subsets in different types of urticaria [Elektronische Daten] [B. Czarnetzki, G. Zwadlo-Klarwasser, E. Bröcker, C. Sorg] Summary: Biopsy specimens from lesional and uninvolved skin of nine patients with delayed pressure urticaria, three patients with acute urticaria, six patients with chronic recurrent urticaria, and four patients with urticaria pigmentosa were analyzed by routine histology and by immunochemistry for their reactivity with monoclonal antibodies to three different subsets of macrophages. Skin from 12 healthy volunteers served as control. Uninvolved skin of patients did not differ from that of healthy volunteers. An antibody against activated macrophages (27E10) was reactive to a marked extent with macrophages in wheals of pressure urticaria, more variably in acute and chronic urticaria, and practically not at all in urticaria pigmentosa. Antibodies with specificities for macrophages in healing (RM3/1) and normal (25F9) tissue reacted more markedly in all but pressure urticaria lesions, compared with normal skin. These findings indicate an active involvement of inflammatory macrophages in whealing reactions while these cells play apparently no role in cutaneous mast cell proliferation (urticaria pigmentosa). Springer-Verlag, 1990 Macrophages nationallicence Urticaria nationallicence Inflammation nationallicence Immunocytochemistry nationallicence Czarnetzki B. Departments of Clinical and Experimental Dermatology, University Clinics, Münster, FRG aut Zwadlo-Klarwasser G. Departments of Clinical and Experimental Dermatology, University Clinics, Münster, FRG aut Bröcker E. Departments of Clinical and Experimental Dermatology, University Clinics, Münster, FRG aut Sorg C. Departments of Clinical and Experimental Dermatology, University Clinics, Münster, FRG aut Archives of Dermatological Research Springer-Verlag 282/2(1990-01-01), 93-97 0340-3696 282:2<93 1990 282 403 https://doi.org/10.1007/BF00493465 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00493465 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Czarnetzki B. Departments of Clinical and Experimental Dermatology, University Clinics, Münster, FRG aut NATIONALLICENCE 700 1- Zwadlo-Klarwasser G. Departments of Clinical and Experimental Dermatology, University Clinics, Münster, FRG aut NATIONALLICENCE 700 1- Bröcker E. Departments of Clinical and Experimental Dermatology, University Clinics, Münster, FRG aut NATIONALLICENCE 700 1- Sorg C. Departments of Clinical and Experimental Dermatology, University Clinics, Münster, FRG aut NATIONALLICENCE 773 0- Archives of Dermatological Research Springer-Verlag 282/2(1990-01-01), 93-97 0340-3696 282:2<93 1990 282 403 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer