caa a22 4500 465774075 CHVBK 20180323111937.0 cr unu---uuuuu 170327e19900101xx s 000 0 eng 10.1007/BF00412736 doi (NATIONALLICENCE)springer-10.1007/BF00412736 State of leukocyte adhesiveness/aggregation in the peripheral blood of pemphigus and psoriatic patients [Elektronische Daten] [A. Filhaber, S. Berliner, J. Lidor, M. Sandbank, M. Aronson, M. David] Summary: The purpose of this study was to assess the role of leukocyte adherence in the pathogenesis of the psoriatic lesion. Use was made of the fact that psoriasis and pemphigus differ considerably as to the presence of leukocytes in the respective lesions: abundance in psoriasis, and absence in pemphigus. The state of leukocyte adhesiveness/aggregation (LAA) was determined in the peripheral blood of 56 patients with psoriasis and 31 patients with pemphigus. Both classes of patients were subdivided into two categories according to the severity of the disease. It was found that in both diseases elevated values of LAA were obtained in the severe cases, whereas the mild cases did not differ significantly from normal controls. Thus, in psoriasis mean LAA values of 9.5%±8% were recorded in the severe patients and 5.5%±4.2% in the mild cases (p=0.01), while in pemphigus the values were 15%±9.6% and 6.6%±3.7% respectively (p=0.03). It is concluded that LAA per se does not play a primary role in causing the psoriatic lesion. Springer-Verlag, 1990 Leukocyte aggregation nationallicence Pemphigus nationallicence Psoriasis nationallicence Filhaber A. Department of Dermatology, Beilinson Medical Center, 49 100, Petah Tikva aut Berliner S. Internal Medicine "D”, Beilinson Medical Center, 49 100, Petah Tikva aut Lidor J. Department of Dermatology, Beilinson Medical Center, 49 100, Petah Tikva aut Sandbank M. Department of Dermatology, Beilinson Medical Center, 49 100, Petah Tikva aut Aronson M. Department of Cell Biology, Sackler Faculty of Medicine, Tel Aviv University, 69978, Tel Aviv, Israel aut David M. Department of Dermatology, Beilinson Medical Center, 49 100, Petah Tikva aut Archives of Dermatological Research Springer-Verlag 281/8(1990-01-01), 519-520 0340-3696 281:8<519 1990 281 403 https://doi.org/10.1007/BF00412736 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00412736 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Filhaber A. Department of Dermatology, Beilinson Medical Center, 49 100, Petah Tikva aut NATIONALLICENCE 700 1- Berliner S. Internal Medicine "D”, Beilinson Medical Center, 49 100, Petah Tikva aut NATIONALLICENCE 700 1- Lidor J. Department of Dermatology, Beilinson Medical Center, 49 100, Petah Tikva aut NATIONALLICENCE 700 1- Sandbank M. Department of Dermatology, Beilinson Medical Center, 49 100, Petah Tikva aut NATIONALLICENCE 700 1- Aronson M. Department of Cell Biology, Sackler Faculty of Medicine, Tel Aviv University, 69978, Tel Aviv, Israel aut NATIONALLICENCE 700 1- David M. Department of Dermatology, Beilinson Medical Center, 49 100, Petah Tikva aut NATIONALLICENCE 773 0- Archives of Dermatological Research Springer-Verlag 281/8(1990-01-01), 519-520 0340-3696 281:8<519 1990 281 403 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer