caa a22 4500 465777147 CHVBK 20180323111945.0 cr unu---uuuuu 170327e19900101xx s 000 0 eng 10.1007/BF02764293 doi (NATIONALLICENCE)springer-10.1007/BF02764293 Immunohistochemical characterization of epithelial cells in human lacrimal glands [Elektronische Daten] I. Normal major and accessory lacrimal glands [Nadarajah Vigneswaran, Carl Wilk, Angelika Heese, Otto Hornstein, Gottfried Naumann] Expression patterns of cytokeratins (CKs), actin, lactoferrin (Lf), lysozyme (Ly), vimentin, and S-100 protein were immunohistochemically examined in paraffin sections from eight normal major and accessory lacrimal glands (LGs). Luminal duct cells and a number of secretory cells stained with the antibodies (ABs) KL1 and Pkk1 (CK 7, 8, 17, 18), while basal duct and myoepithelial cells reacted with the AB 34βE12 (CK 5). Myoepithelial cells expressing CK 5 and actin were restricted to acini and intralobular ducts, and their number was greater in major LGs than accessory ones. Lf and Ly were found in 50%-75% of acini and intralobular ducts. Vimentin was absent in parenchyma of LGs. S-100 protein reaction was observed in a number of acinar and luminal duct cells of major LGs whereas epithelia of accessory LGs remained negative. Distribution patterns of CKs, Lf, and Ly in major and accessory LGs are identical. The difference with respect to the number of myoepithelial cells as well as S-100 protein reactivity between major and accessory LGs reactivity appeared to be relevant to the differences in their secretory mechanisms and local environment. Springer-Verlag, 1990 Vigneswaran Nadarajah Dermatologische Klinik und Poliklinik der Universität Erlangen-Nürnberg, Hartmannstrasse 14, D-8520, Erlangen, Federal Republic of Germany aut Wilk Carl Augenklinik mit Poliklinik der Universität Erlangen-Nürnberg, Schwabachanlage 6, D-8520, Erlangen, Federal Republic of Germany aut Heese Angelika Dermatologische Klinik und Poliklinik der Universität Erlangen-Nürnberg, Hartmannstrasse 14, D-8520, Erlangen, Federal Republic of Germany aut Hornstein Otto Dermatologische Klinik und Poliklinik der Universität Erlangen-Nürnberg, Hartmannstrasse 14, D-8520, Erlangen, Federal Republic of Germany aut Naumann Gottfried Augenklinik mit Poliklinik der Universität Erlangen-Nürnberg, Schwabachanlage 6, D-8520, Erlangen, Federal Republic of Germany aut Graefe's Archive for Clinical and Experimental Ophthalmology Springer-Verlag 228/1(1990-01-01), 58-64 0721-832X 228:1<58 1990 228 417 https://doi.org/10.1007/BF02764293 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02764293 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Vigneswaran Nadarajah Dermatologische Klinik und Poliklinik der Universität Erlangen-Nürnberg, Hartmannstrasse 14, D-8520, Erlangen, Federal Republic of Germany aut NATIONALLICENCE 700 1- Wilk Carl Augenklinik mit Poliklinik der Universität Erlangen-Nürnberg, Schwabachanlage 6, D-8520, Erlangen, Federal Republic of Germany aut NATIONALLICENCE 700 1- Heese Angelika Dermatologische Klinik und Poliklinik der Universität Erlangen-Nürnberg, Hartmannstrasse 14, D-8520, Erlangen, Federal Republic of Germany aut NATIONALLICENCE 700 1- Hornstein Otto Dermatologische Klinik und Poliklinik der Universität Erlangen-Nürnberg, Hartmannstrasse 14, D-8520, Erlangen, Federal Republic of Germany aut NATIONALLICENCE 700 1- Naumann Gottfried Augenklinik mit Poliklinik der Universität Erlangen-Nürnberg, Schwabachanlage 6, D-8520, Erlangen, Federal Republic of Germany aut NATIONALLICENCE 773 0- Graefe's Archive for Clinical and Experimental Ophthalmology Springer-Verlag 228/1(1990-01-01), 58-64 0721-832X 228:1<58 1990 228 417 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer