caa a22 4500 46577721X CHVBK 20180323111945.0 cr unu---uuuuu 170327e19900101xx s 000 0 eng 10.1007/BF02764288 doi (NATIONALLICENCE)springer-10.1007/BF02764288 Diffuse necrotizing retinochoroiditis in a child with AIDS and toxoplasmic encephalitis [Elektronische Daten] [Ferdinando Bottoni, Pietro Gonnella, Alessandro Autelitano, Nicola Orzalesi] We examined a child with a human immunodeficiency virus (HIV) infection who at 15 months of age developed acute encephalitis, followed 1 week later by a diffuse, uniocular retinochoroiditis. The clinical picture in the right eye was characterized by the occurrence of some intraretinal hemorrhages; punctate, yellow-white, outer retinal lesions temporal to the macula; and a quadrantal, white area of necrotic retina located superotemporally. — The vitreous was remarkably clear, and the left eye was normal. Fluorescein angiography revealed small spots of late hyperfluorescence, vasculitis in the posterior pole, and a persistently hypofluorescent quadrantal superotemporal area.Toxoplasma IgM antibodies that were absent 1 week after birth became detectable in the serum and the cerebrospinal fluid. Serological testing for cytomegalovirus was negative. Neurological signs improved on a specific therapy (pyrimethamine and sulfamethopirazine), but the patient died 2 months later of disseminated cytomegalovirus infection. Springer-Verlag, 1990 Bottoni Ferdinando Institute of Biomedical Science, University Eye Clinic, S. Paolo Hospital, I-20144, Milano, Italy aut Gonnella Pietro Institute of Biomedical Science, University Eye Clinic, S. Paolo Hospital, I-20144, Milano, Italy aut Autelitano Alessandro Institute of Biomedical Science, University Eye Clinic, S. Paolo Hospital, I-20144, Milano, Italy aut Orzalesi Nicola Institute of Biomedical Science, University Eye Clinic, S. Paolo Hospital, I-20144, Milano, Italy aut Graefe's Archive for Clinical and Experimental Ophthalmology Springer-Verlag 228/1(1990-01-01), 36-39 0721-832X 228:1<36 1990 228 417 https://doi.org/10.1007/BF02764288 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02764288 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bottoni Ferdinando Institute of Biomedical Science, University Eye Clinic, S. Paolo Hospital, I-20144, Milano, Italy aut NATIONALLICENCE 700 1- Gonnella Pietro Institute of Biomedical Science, University Eye Clinic, S. Paolo Hospital, I-20144, Milano, Italy aut NATIONALLICENCE 700 1- Autelitano Alessandro Institute of Biomedical Science, University Eye Clinic, S. Paolo Hospital, I-20144, Milano, Italy aut NATIONALLICENCE 700 1- Orzalesi Nicola Institute of Biomedical Science, University Eye Clinic, S. Paolo Hospital, I-20144, Milano, Italy aut NATIONALLICENCE 773 0- Graefe's Archive for Clinical and Experimental Ophthalmology Springer-Verlag 228/1(1990-01-01), 36-39 0721-832X 228:1<36 1990 228 417 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer