caa a22 4500 46577752X CHVBK 20180323111946.0 cr unu---uuuuu 170327e19901101xx s 000 0 eng 10.1007/BF00918489 doi (NATIONALLICENCE)springer-10.1007/BF00918489 Evaluation of radiation therapy for experimental proliferative vitreoretinopathy in rabbits [Elektronische Daten] [Shoji Kuriyama, Teruyo Ohuchi, Nagahisa Yoshimura, Yoshibito Honda, Masahiro Hiraoka, Mitsuyuki Abe] We evaluated effects of radiation therapy on experimental proliferative vitreoretinopathy (PVR) induced in rabbits by double gas compression of the vitreous followed by homologous dermal-skin fibroblast injection. Electrons were irradiated in two rabbit groups. Group A animals (20 eyes) received 1000 cGy of irradiation immediately after cell injection; group B rabbits (9 eyes), which showed pucker formation 7 days after cell injection, were irradiated on that day at the same dose as was given to group A rabbits. Control animals (14 eyes) were not irradiated. The incidences of traction retinal detachment on day 28 were: control, 86%; group A, 10%; and group B, 22%. There were statistically significant differences between control and group A values and between control and group B values. No significant difference was found between group A and group B. Irradiation of 1000 cGy did not alter the histological picture of experimental PVR. The results showed that radiation suppressed the development of PVR when applied not only immediately after cell injection but also during pucker stages. Springer-Verlag, 1990 Kuriyama Shoji Department of Ophthalmology, Kyoto University Faculty of Medicine, 606, Kyoto, Japan aut Ohuchi Teruyo Department of Ophthalmology, Kyoto University Faculty of Medicine, 606, Kyoto, Japan aut Yoshimura Nagahisa Department of Ophthalmology, Kyoto University Faculty of Medicine, 606, Kyoto, Japan aut Honda Yoshibito Department of Ophthalmology, Kyoto University Faculty of Medicine, 606, Kyoto, Japan aut Hiraoka Masahiro Department of Radiology, Kyoto University Faculty of Medicine, 606, Kyoto, Japan aut Abe Mitsuyuki Department of Radiology, Kyoto University Faculty of Medicine, 606, Kyoto, Japan aut Graefe's Archive for Clinical and Experimental Ophthalmology Springer-Verlag 228/6(1990-11-01), 552-555 0721-832X 228:6<552 1990 228 417 https://doi.org/10.1007/BF00918489 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00918489 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kuriyama Shoji Department of Ophthalmology, Kyoto University Faculty of Medicine, 606, Kyoto, Japan aut NATIONALLICENCE 700 1- Ohuchi Teruyo Department of Ophthalmology, Kyoto University Faculty of Medicine, 606, Kyoto, Japan aut NATIONALLICENCE 700 1- Yoshimura Nagahisa Department of Ophthalmology, Kyoto University Faculty of Medicine, 606, Kyoto, Japan aut NATIONALLICENCE 700 1- Honda Yoshibito Department of Ophthalmology, Kyoto University Faculty of Medicine, 606, Kyoto, Japan aut NATIONALLICENCE 700 1- Hiraoka Masahiro Department of Radiology, Kyoto University Faculty of Medicine, 606, Kyoto, Japan aut NATIONALLICENCE 700 1- Abe Mitsuyuki Department of Radiology, Kyoto University Faculty of Medicine, 606, Kyoto, Japan aut NATIONALLICENCE 773 0- Graefe's Archive for Clinical and Experimental Ophthalmology Springer-Verlag 228/6(1990-11-01), 552-555 0721-832X 228:6<552 1990 228 417 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer