caa a22 4500 465777619 CHVBK 20180323111946.0 cr unu---uuuuu 170327e19900501xx s 000 0 eng 10.1007/BF00920022 doi (NATIONALLICENCE)springer-10.1007/BF00920022 Differentiation of ischemic from non-ischemic central retinal vein occlusion during the early acute phase [Elektronische Daten] [Sohan Hayreh, Marie Klugman, Meena Beri, Alan Kimura, Patricia Podhajsky] We investigated prospectively in 128 patients (140 eyes) the role of six routine clinical tests in the differentiation of ischemic central retinal vein occlusion (CRVO) from non-ischemic CRVO during its early acute phase. There were fourfunctional tests [visual acuity, visual fields, relative afferent pupillary defect (RAPID), electroretinography (ERG)] and twomorphologic tests (ophthalmoscopy and fluorescein fundus angiography). We found that none of the six tests had 100% sensitivity and specificity in such a differentiation during the early, acute phase, so that no one test can be considered a "gold standard”; however, combined information from all six is almost always reliable. Overall, the four functional tests proved far superior to the two morphologic tests in differentiating ischemic from non-ischemic CRVO: RAPID was most reliable in uniocular CRVO (with a normal fellow eye), followed closely by ERG in all cases; combined information from RAPID and ERG differentiated 97% of cases; perimetry was the next most reliable, followed by visual acuity. The two morphologic tests performed worst; fluorescein angiography provided either no information at all on retinal capillary nonperfusion (in at least one-third of the eyes during the early, acute phase) because of multiple limitations, or sometimes provided misleading information. Ophthalmoscopic appearance is the least reliable, most misleading parameter. Springer-Verlag, 1990 Hayreh Sohan Department of Ophthalmology, University of Iowa, 52242, Iowa City, IA, USA aut Klugman Marie Department of Preventive Medicine (Biostatistics), University of Iowa, 52242, Iowa City, IA, USA aut Beri Meena Department of Ophthalmology, University of Iowa, 52242, Iowa City, IA, USA aut Kimura Alan Department of Ophthalmology, University of Iowa, 52242, Iowa City, IA, USA aut Podhajsky Patricia Department of Ophthalmology, University of Iowa, 52242, Iowa City, IA, USA aut Graefe's Archive for Clinical and Experimental Ophthalmology Springer-Verlag 228/3(1990-05-01), 201-217 0721-832X 228:3<201 1990 228 417 https://doi.org/10.1007/BF00920022 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00920022 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hayreh Sohan Department of Ophthalmology, University of Iowa, 52242, Iowa City, IA, USA aut NATIONALLICENCE 700 1- Klugman Marie Department of Preventive Medicine (Biostatistics), University of Iowa, 52242, Iowa City, IA, USA aut NATIONALLICENCE 700 1- Beri Meena Department of Ophthalmology, University of Iowa, 52242, Iowa City, IA, USA aut NATIONALLICENCE 700 1- Kimura Alan Department of Ophthalmology, University of Iowa, 52242, Iowa City, IA, USA aut NATIONALLICENCE 700 1- Podhajsky Patricia Department of Ophthalmology, University of Iowa, 52242, Iowa City, IA, USA aut NATIONALLICENCE 773 0- Graefe's Archive for Clinical and Experimental Ophthalmology Springer-Verlag 228/3(1990-05-01), 201-217 0721-832X 228:3<201 1990 228 417 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer