caa a22 4500 465777643 CHVBK 20180323111946.0 cr unu---uuuuu 170327e19900501xx s 000 0 eng 10.1007/BF00920031 doi (NATIONALLICENCE)springer-10.1007/BF00920031 Angiogenesis in normal human retinal development the involvement of astrocytes and macrophages [Elektronische Daten] [Philip Penfold, Jan Provis, Michele Madigan, Diana van Driel, Francis Billson] Recent studies have suggested a role for mononuclear phagocytes series (MPS) cells in neovascularisation associated with retinal pathology and experimentally induced subretinal neovascularisation. The present study is concerned with the normal development of the human retinal vasculature. Morphological details are provided of developing vascular structures including the formation of tight junctions and canalisation of angioblast cords. The relationships of astrocytes and pericytes to developing structures and the presence of a perivascular collagenous matrix are described. Ultrastructural and histochemcal analyses reveal an association between MPS cells and developing vascular structures. It is suggested that MPS cells may influence angiogenesis in normal retinal development, as well as in retinal pathology. Springer-Verlag, 1990 Penfold Philip Save Sight and Eye Health Institute, Department of Clinical Ophthalmology, University of Sydney, Sydney, Australia aut Provis Jan Save Sight and Eye Health Institute, Department of Anatomy, University of Sydney, Sydney, Australia aut Madigan Michele Save Sight and Eye Health Institute, Department of Clinical Ophthalmology, University of Sydney, Sydney, Australia aut van Driel Diana Save Sight and Eye Health Institute, Department of Clinical Ophthalmology, University of Sydney, Sydney, Australia aut Billson Francis aut Graefe's Archive for Clinical and Experimental Ophthalmology Springer-Verlag 228/3(1990-05-01), 255-263 0721-832X 228:3<255 1990 228 417 https://doi.org/10.1007/BF00920031 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00920031 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Penfold Philip Save Sight and Eye Health Institute, Department of Clinical Ophthalmology, University of Sydney, Sydney, Australia aut NATIONALLICENCE 700 1- Provis Jan Save Sight and Eye Health Institute, Department of Anatomy, University of Sydney, Sydney, Australia aut NATIONALLICENCE 700 1- Madigan Michele Save Sight and Eye Health Institute, Department of Clinical Ophthalmology, University of Sydney, Sydney, Australia aut NATIONALLICENCE 700 1- van Driel Diana Save Sight and Eye Health Institute, Department of Clinical Ophthalmology, University of Sydney, Sydney, Australia aut NATIONALLICENCE 700 1- Billson Francis aut NATIONALLICENCE 773 0- Graefe's Archive for Clinical and Experimental Ophthalmology Springer-Verlag 228/3(1990-05-01), 255-263 0721-832X 228:3<255 1990 228 417 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer