caa a22 4500 465777651 CHVBK 20180323111946.0 cr unu---uuuuu 170327e19900501xx s 000 0 eng 10.1007/BF00920029 doi (NATIONALLICENCE)springer-10.1007/BF00920029 Clinical course and pathologic features of conjunctival non-Hodgkin's lymphoma [Elektronische Daten] A report of six cases [Hussein Khalil, Rob de Keizer, Philip Kluin, Hanneke Kluin-Nelemans, Didi de Wolff-Rouendaal] Six patients with conjunctival non-Hodgkin's lymphoma (NHL) were evaluated. In all six cases the conjunctiva was the primary site of clinical presentation; four cases involved low-grade malignancy and two, intermediate-grade malignancy, according to the International Working Formulation. The disease developed within a short period of time to stage IV The poor response to therapy revealed a worse prognosis than would be expected according to the histopathologic classification. Four of the six patients died of NHL, three of them within 15 months. Comparison of these 6 cases with a group of 15 patients with orbital NHL revealed a much better prognosis in the latter patients. In spite of the fact that 4 of the 15 orbital cases showed NHL of high-grade malignancy, only 2 of them died of the lymphoma. Therefore, conjunctival NHL requires a fast and adequate diagnostic and therapeutic approach. Springer-Verlag, 1990 Khalil Hussein Department of Ophthalmology, University Hospital, Rijnsburgerweg 10, 2333 AA, Leiden, The Netherlands aut de Keizer Rob Department of Ophthalmology, University Hospital, Rijnsburgerweg 10, 2333 AA, Leiden, The Netherlands aut Kluin Philip Department of Pathology, Leiden University, Wassenaarseweg 62, 2333 AL, Leiden, The Netherlands aut Kluin-Nelemans Hanneke Department of Hematology, University Hospital, Rijnsburgerweg 10, 2333 AA, Leiden, The Netherlands aut de Wolff-Rouendaal Didi Department of Ophthalmology, University Hospital, Rijnsburgerweg 10, 2333 AA, Leiden, The Netherlands aut Graefe's Archive for Clinical and Experimental Ophthalmology Springer-Verlag 228/3(1990-05-01), 246-251 0721-832X 228:3<246 1990 228 417 https://doi.org/10.1007/BF00920029 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00920029 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Khalil Hussein Department of Ophthalmology, University Hospital, Rijnsburgerweg 10, 2333 AA, Leiden, The Netherlands aut NATIONALLICENCE 700 1- de Keizer Rob Department of Ophthalmology, University Hospital, Rijnsburgerweg 10, 2333 AA, Leiden, The Netherlands aut NATIONALLICENCE 700 1- Kluin Philip Department of Pathology, Leiden University, Wassenaarseweg 62, 2333 AL, Leiden, The Netherlands aut NATIONALLICENCE 700 1- Kluin-Nelemans Hanneke Department of Hematology, University Hospital, Rijnsburgerweg 10, 2333 AA, Leiden, The Netherlands aut NATIONALLICENCE 700 1- de Wolff-Rouendaal Didi Department of Ophthalmology, University Hospital, Rijnsburgerweg 10, 2333 AA, Leiden, The Netherlands aut NATIONALLICENCE 773 0- Graefe's Archive for Clinical and Experimental Ophthalmology Springer-Verlag 228/3(1990-05-01), 246-251 0721-832X 228:3<246 1990 228 417 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer