caa a22 4500 465777872 CHVBK 20180323111947.0 cr unu---uuuuu 170327e19900701xx s 000 0 eng 10.1007/BF00920065 doi (NATIONALLICENCE)springer-10.1007/BF00920065 Formation of "vessel-like” structures by retinal capillary endothelial cells in culture [Elektronische Daten] [Mike Boulton, Hong Chai Wong, Steve Rothery, John Marshall] The formation of "vessel-like” structures has been previously reported in cultures of endothelial cells from both large and small vessels. In this study the formation of such tubular structures was observed in post-confluent cultures of bovine retinal microvascular endothelial cells. As the cells became postconfluent, cell dropout occurred and the remaining islands of cells were observed to be interconnected by cords. Electron microscopy demonstrated that each cord consisted of a continuous lumen surrounded by one or more endothelial cells. The mechanisms of in vitro "vessel formation” by retinal endothelial cells do not appear to relate to either those of embryonic retinal vascularisation or those associated with retinal neovascularisation and may be an unrelated phenomenon only expressed in vitro. Springer-Verlag, 1990 Boulton Mike Department of Clinical Ophthalmology, Institute of Ophthalmology, Judd Street, WC1H 9QS, London, UK aut Chai Wong Hong Department of Clinical Ophthalmology, Institute of Ophthalmology, Judd Street, WC1H 9QS, London, UK aut Rothery Steve Department of Clinical Ophthalmology, Institute of Ophthalmology, Judd Street, WC1H 9QS, London, UK aut Marshall John Department of Clinical Ophthalmology, Institute of Ophthalmology, Judd Street, WC1H 9QS, London, UK aut Graefe's Archive for Clinical and Experimental Ophthalmology Springer-Verlag 228/4(1990-07-01), 377-381 0721-832X 228:4<377 1990 228 417 https://doi.org/10.1007/BF00920065 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00920065 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Boulton Mike Department of Clinical Ophthalmology, Institute of Ophthalmology, Judd Street, WC1H 9QS, London, UK aut NATIONALLICENCE 700 1- Chai Wong Hong Department of Clinical Ophthalmology, Institute of Ophthalmology, Judd Street, WC1H 9QS, London, UK aut NATIONALLICENCE 700 1- Rothery Steve Department of Clinical Ophthalmology, Institute of Ophthalmology, Judd Street, WC1H 9QS, London, UK aut NATIONALLICENCE 700 1- Marshall John Department of Clinical Ophthalmology, Institute of Ophthalmology, Judd Street, WC1H 9QS, London, UK aut NATIONALLICENCE 773 0- Graefe's Archive for Clinical and Experimental Ophthalmology Springer-Verlag 228/4(1990-07-01), 377-381 0721-832X 228:4<377 1990 228 417 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer