caa a22 4500 465777988 CHVBK 20180323111947.0 cr unu---uuuuu 170327e19900901xx s 000 0 eng 10.1007/BF00927258 doi (NATIONALLICENCE)springer-10.1007/BF00927258 Retinal circulation times in quantitative fluorescein angiography [Elektronische Daten] [Tetsuro Koyama, Nobuhiko Matsuo, Keiichi Shimizu, Masayoshi Mihara, Yozo Tsuchida, Sebastian Wolf, Martin Reim] We tried to obtain an overview of the quantitative state of the retinal circulation. Optical density measurements by an image analyzer were performed on video fluorescein angiograms for the determination of dye-dilution curves. To ensure that curves with a sharp peak were obtained, 1 ml sodium fluorescein 10% was flushed with 20 ml physiological saline. From dilution curves of a retinal arteriole and the corresponding venule, various retinal circulation times, T (x) (x=1, 25, 50, 75, and 100) and Tm, were calculated. T(1) corresponds to the difference in the time of initial dye appearance; T(50), to the so-called half-maxim time difference; T(100), to the difference in the time to peak intensity; and Tm, to the mean circulation time. T(50) showed the best reproducibility when it was examined at 49 retinal regions of 10 healthy volunteers with a double video-fluorescein angiogram that was obtained within 1 min. Normal values (mean ± SD) at the temporal superior region of 37 healthy volunteers were as follows: T (1) = 0.87 ± 0.66 s, T(25)=1.52±0.48 s, T(50)=1.83±0.50 s, T(75)=2.12±0.56 s, T(t00) = 2.73±0.76 s, and Tm = 2.69±1.25 s. We believe that these values give a general overview of the quantitative state of normal retinal circulation. Springer-Verlag, 1990 Koyama Tetsuro Department of Ophthalmology, Okayama University Medical School, 2-5-1 Shikatacho, 700, Okayama, Japan aut Matsuo Nobuhiko Department of Ophthalmology, Okayama University Medical School, 2-5-1 Shikatacho, 700, Okayama, Japan aut Shimizu Keiichi Department of Ophthalmology, Okayama University Medical School, 2-5-1 Shikatacho, 700, Okayama, Japan aut Mihara Masayoshi Department of Ophthalmology, Okayama University Medical School, 2-5-1 Shikatacho, 700, Okayama, Japan aut Tsuchida Yozo Department of Ophthalmology, Okayama University Medical School, 2-5-1 Shikatacho, 700, Okayama, Japan aut Wolf Sebastian Augenklinik der Rheinisch-Westfaelischen Technischen Hochschule Aachen, Pauwelsstrasse, D-5100, Aachen, Germany aut Reim Martin Augenklinik der Rheinisch-Westfaelischen Technischen Hochschule Aachen, Pauwelsstrasse, D-5100, Aachen, Germany aut Graefe's Archive for Clinical and Experimental Ophthalmology Springer-Verlag 228/5(1990-09-01), 442-446 0721-832X 228:5<442 1990 228 417 https://doi.org/10.1007/BF00927258 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00927258 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Koyama Tetsuro Department of Ophthalmology, Okayama University Medical School, 2-5-1 Shikatacho, 700, Okayama, Japan aut NATIONALLICENCE 700 1- Matsuo Nobuhiko Department of Ophthalmology, Okayama University Medical School, 2-5-1 Shikatacho, 700, Okayama, Japan aut NATIONALLICENCE 700 1- Shimizu Keiichi Department of Ophthalmology, Okayama University Medical School, 2-5-1 Shikatacho, 700, Okayama, Japan aut NATIONALLICENCE 700 1- Mihara Masayoshi Department of Ophthalmology, Okayama University Medical School, 2-5-1 Shikatacho, 700, Okayama, Japan aut NATIONALLICENCE 700 1- Tsuchida Yozo Department of Ophthalmology, Okayama University Medical School, 2-5-1 Shikatacho, 700, Okayama, Japan aut NATIONALLICENCE 700 1- Wolf Sebastian Augenklinik der Rheinisch-Westfaelischen Technischen Hochschule Aachen, Pauwelsstrasse, D-5100, Aachen, Germany aut NATIONALLICENCE 700 1- Reim Martin Augenklinik der Rheinisch-Westfaelischen Technischen Hochschule Aachen, Pauwelsstrasse, D-5100, Aachen, Germany aut NATIONALLICENCE 773 0- Graefe's Archive for Clinical and Experimental Ophthalmology Springer-Verlag 228/5(1990-09-01), 442-446 0721-832X 228:5<442 1990 228 417 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer