caa a22 4500 465778011 CHVBK 20180323111947.0 cr unu---uuuuu 170327e19900901xx s 000 0 eng 10.1007/BF00927266 doi (NATIONALLICENCE)springer-10.1007/BF00927266 Clinicopathological findings 11 months after implantation of a functioning aqueous-drainage silicone implant [Elektronische Daten] [Wolfgang Philipp, Günther Klima, Klaus Miller] An aqueous-drainage silicone device was implanted in a 57-year-old diabetic patient with neovascular glaucoma after failure of conventional therapy. Postoperative intraocular pressure (IOP) was well controlled, ranging between 10 and 20 mm Hg without the use of supplemental agents. Despite the normal IOP, the eye became painful and amaurotic 11 months after implantation due to progression of the retinopathy accompanied by the development of severe tractional retinal detachment. Enucleation was performed and the eye underwent histopathological examination. The filtering bleb around the silicone plate of the implant on the equatorial sclera was lined with a thick layer of collagenous connective tissue. Numerous microcystic spaces could be seen in the bleb wall by light microscopy. Electron microscopy confirmed this finding; in addition, only a meshwork of collagen fibre-like bundles was visible at some areas of the innermost bleb wall. Control of IOP in spite of bleb fibrosis in this particular case may have been due to a loss of matrix components and to the formation of microcystic spaces in the bleb wall, which seem likely to be channels for the passage of aqueous humor. Springer-Verlag, 1990 Philipp Wolfgang Universitäts-Klinik für Augenheilkunde Innsbruck, Anichstrasse 35, A-6020, Innsbruck, Austria aut Klima Günther Institut für Histologic und Embryologic der Universität Innsbruck, Müllerstrasse 59, A-6020, Innsbruck, Austria aut Miller Klaus Universitäts-Klinik für Augenheilkunde Innsbruck, Anichstrasse 35, A-6020, Innsbruck, Austria aut Graefe's Archive for Clinical and Experimental Ophthalmology Springer-Verlag 228/5(1990-09-01), 481-486 0721-832X 228:5<481 1990 228 417 https://doi.org/10.1007/BF00927266 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00927266 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Philipp Wolfgang Universitäts-Klinik für Augenheilkunde Innsbruck, Anichstrasse 35, A-6020, Innsbruck, Austria aut NATIONALLICENCE 700 1- Klima Günther Institut für Histologic und Embryologic der Universität Innsbruck, Müllerstrasse 59, A-6020, Innsbruck, Austria aut NATIONALLICENCE 700 1- Miller Klaus Universitäts-Klinik für Augenheilkunde Innsbruck, Anichstrasse 35, A-6020, Innsbruck, Austria aut NATIONALLICENCE 773 0- Graefe's Archive for Clinical and Experimental Ophthalmology Springer-Verlag 228/5(1990-09-01), 481-486 0721-832X 228:5<481 1990 228 417 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer