caa a22 4500 46577833X CHVBK 20180323111948.0 cr unu---uuuuu 170327e19900301xx s 000 0 eng 10.1007/BF00935716 doi (NATIONALLICENCE)springer-10.1007/BF00935716 Medical treatment of senile cataract: Clinical investigation of bendazac-lysine using objective and subjective methods [Elektronische Daten] [Patrizia Baraldi, Sergio Fonda, Piergiorgio Toschi, Barbara Benassi, Maria Luppi, Alessandro Penne, Carlo Mazza, Ernesto Bocca] A modified Zeiss slit lamp coupled with a digital image-processing system was used to evaluate objectively changes in lens transparency over 1 year at 4-month intervals in 150 eyes of 92 patients affected by early senile cataract. A total of 59 patients were treated daily with 1.5 g bendazac-lysine, and 33 patients constituted the control group. At follow-up, visual acuity was also tested using Suellen letter charts at variable contrast to provide an additional parameter closer to traditional methods. Results indicate that the minimal angle of resolution at 10% contrast (MAR10) and the mean gray-level value of the lens image obtained by retroillumination (MLR) are sensitive to early changes in lens transparency. Using MAR10 as a parameter, the control group showed a significant, progressive worsening of the lens status over 12 months, whereas the treated group exhibited no significant changes. MRL indicated the same behaviour as MAR10, although lens damage was detected later in the control group. The results show that bendazac-lysine may delay the formation of lens opacities. Springer-Verlag, 1990 Baraldi Patrizia Laboratorio di Bioingegneria and Clinica Oculistica, Università di Modena, Via del Pozzo 71, 1-41100, Modena, Italy aut Fonda Sergio Laboratorio di Bioingegneria and Clinica Oculistica, Università di Modena, Via del Pozzo 71, 1-41100, Modena, Italy aut Toschi Piergiorgio Laboratorio di Bioingegneria and Clinica Oculistica, Università di Modena, Via del Pozzo 71, 1-41100, Modena, Italy aut Benassi Barbara Laboratorio di Bioingegneria and Clinica Oculistica, Università di Modena, Via del Pozzo 71, 1-41100, Modena, Italy aut Luppi Maria Laboratorio di Bioingegneria and Clinica Oculistica, Università di Modena, Via del Pozzo 71, 1-41100, Modena, Italy aut Penne Alessandro Laboratorio di Bioingegneria and Clinica Oculistica, Università di Modena, Via del Pozzo 71, 1-41100, Modena, Italy aut Mazza Carlo Laboratorio di Bioingegneria and Clinica Oculistica, Università di Modena, Via del Pozzo 71, 1-41100, Modena, Italy aut Bocca Ernesto Laboratorio di Bioingegneria and Clinica Oculistica, Università di Modena, Via del Pozzo 71, 1-41100, Modena, Italy aut Graefe's Archive for Clinical and Experimental Ophthalmology Springer-Verlag 228/2(1990-03-01), 105-111 0721-832X 228:2<105 1990 228 417 https://doi.org/10.1007/BF00935716 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00935716 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Baraldi Patrizia Laboratorio di Bioingegneria and Clinica Oculistica, Università di Modena, Via del Pozzo 71, 1-41100, Modena, Italy aut NATIONALLICENCE 700 1- Fonda Sergio Laboratorio di Bioingegneria and Clinica Oculistica, Università di Modena, Via del Pozzo 71, 1-41100, Modena, Italy aut NATIONALLICENCE 700 1- Toschi Piergiorgio Laboratorio di Bioingegneria and Clinica Oculistica, Università di Modena, Via del Pozzo 71, 1-41100, Modena, Italy aut NATIONALLICENCE 700 1- Benassi Barbara Laboratorio di Bioingegneria and Clinica Oculistica, Università di Modena, Via del Pozzo 71, 1-41100, Modena, Italy aut NATIONALLICENCE 700 1- Luppi Maria Laboratorio di Bioingegneria and Clinica Oculistica, Università di Modena, Via del Pozzo 71, 1-41100, Modena, Italy aut NATIONALLICENCE 700 1- Penne Alessandro Laboratorio di Bioingegneria and Clinica Oculistica, Università di Modena, Via del Pozzo 71, 1-41100, Modena, Italy aut NATIONALLICENCE 700 1- Mazza Carlo Laboratorio di Bioingegneria and Clinica Oculistica, Università di Modena, Via del Pozzo 71, 1-41100, Modena, Italy aut NATIONALLICENCE 700 1- Bocca Ernesto Laboratorio di Bioingegneria and Clinica Oculistica, Università di Modena, Via del Pozzo 71, 1-41100, Modena, Italy aut NATIONALLICENCE 773 0- Graefe's Archive for Clinical and Experimental Ophthalmology Springer-Verlag 228/2(1990-03-01), 105-111 0721-832X 228:2<105 1990 228 417 Metadata rights reserved Springer special CC-BY-NC licence nationallicence SWISSBIB 465777244 BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer