caa a22 4500 465783384 CHVBK 20180323112001.0 cr unu---uuuuu 170327e19900501xx s 000 0 eng 10.1007/BF02442678 doi (NATIONALLICENCE)springer-10.1007/BF02442678 Thompson J. University of Birmingham, Department of Anaesthetics, Clinical Research Block, Queen Elizabeth Hospital, B15 2TH, Birmingham, UK aut Performance evaluation of ISFETs and other ISE sensors for whole blood ion assay [Elektronische Daten] [J. Thompson] Performance evaluations of ion-selective field-effect transistors (ISFETs) have been carried out using both quality-control materials and whole arterial blood samples. Comparison of the results from these evaluations suggests that the whole blood evaluation may be more useful when assessing the value of particular sensors for clinical applications. The effect of outliers on the imprecision estimates is demonstrated for ISFETs and ISEs, both graphically and in the calculation of the estimates with an without the outliers present. Estimates of constant and proportional bias, against an alternative sensor, determined from the intercept and slope of the linear regression vary according to the regression method used. The bias estimates obtained for the K+ISFET against the Radiometer KNA1 using ordinary least squares regression are compared with the Deming/Mandel method and the three-group resistant line method of Tukey. The Thorn EMI ISFETs are demonstrated to have acceptable imprecision and only a small bias compared with direct ISE instruments for whole blood assay and can be considered suitable for incorporation into clinical instrumentation. IFMBE, 1990 Bias nationallicence Exploratory graphical analysis nationallicence Imprecision nationallicence ISE nationallicence ISFET nationallicence Outliers nationallicence Performance evaluation nationallicence Resistant regression nationallicence Weighted regression nationallicence Whole blood nationallicence Medical and Biological Engineering and Computing Kluwer Academic Publishers 28/3(1990-05-01), B29-B83 0140-0118 28:3<B29 1990 28 11517 https://doi.org/10.1007/BF02442678 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02442678 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Thompson J. University of Birmingham, Department of Anaesthetics, Clinical Research Block, Queen Elizabeth Hospital, B15 2TH, Birmingham, UK aut NATIONALLICENCE 773 0- Medical and Biological Engineering and Computing Kluwer Academic Publishers 28/3(1990-05-01), B29-B83 0140-0118 28:3<B29 1990 28 11517 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer