caa a22 4500 465783619 CHVBK 20180323112002.0 cr unu---uuuuu 170327e19900701xx s 000 0 eng 10.1007/BF02446146 doi (NATIONALLICENCE)springer-10.1007/BF02446146 Quantification of aortic regurgitation by Doppler echocardiography: a new method evaluated in pigs [Elektronische Daten] [S. Slørdahl, J. Solbakken, H. Piene, B. Angelsen, O. Rossvoll, S. Samstad] We have developed a method to quantify aortic regurgitant orifice and volume, based on measurements of the velocity of the regurgitant jet, aortic systolic flow, the systolic and diastolic arterial pressures, a Windkessel arterial model, and a parameter estimation technique. In six pigs we produced aortic regurgitant flows between 2·1 and 17·8 ml per beat, i.e. regurgitant fractions from 0·06 to 0·58. Pulmonary and aortic flows were measured with electromagnetic flow probes, aortic pressure was measured invasively, and the regurgitant jet velocity was obtained with continuous-wave Doppler. The parameter estimation procedure was based on the Kalman filter principle, resulting primarily in an estimate of the regurgitant orifice area. The area was multiplied by the velocity integral of the regurgitant jet to estimate regurgitant volume. A strong correlation was found between the regurgitant volumes obtained by parameter estimation and the electromagnetic flow measurement. These results from our study in pigs suggest that it may be possible to quantify regurgitant orifice and volume in patients completely noninvasively from Doppler and blood pressure measurements. IFMBE, 1990 Aortic regurgitation nationallicence Doppler ultrasound nationallicence Electromagnetic flow probes nationallicence Parameter estimation nationallicence Regurgitant orifice nationallicence Regurgitant volume nationallicence Windkessel model nationallicence Slørdahl S. Department of Biomedical Engineering, University of Trondheim, 7006, Trondheim, Norway aut Solbakken J. Department of Biomedical Engineering, University of Trondheim, 7006, Trondheim, Norway aut Piene H. Department of Biomedical Engineering, University of Trondheim, 7006, Trondheim, Norway aut Angelsen B. Department of Biomedical Engineering, University of Trondheim, 7006, Trondheim, Norway aut Rossvoll O. Department of Biomedical Engineering, University of Trondheim, 7006, Trondheim, Norway aut Samstad S. Department of Biomedical Engineering, University of Trondheim, 7006, Trondheim, Norway aut Medical and Biological Engineering and Computing Kluwer Academic Publishers 28/4(1990-07-01), 300-305 0140-0118 28:4<300 1990 28 11517 https://doi.org/10.1007/BF02446146 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02446146 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Slørdahl S. Department of Biomedical Engineering, University of Trondheim, 7006, Trondheim, Norway aut NATIONALLICENCE 700 1- Solbakken J. Department of Biomedical Engineering, University of Trondheim, 7006, Trondheim, Norway aut NATIONALLICENCE 700 1- Piene H. Department of Biomedical Engineering, University of Trondheim, 7006, Trondheim, Norway aut NATIONALLICENCE 700 1- Angelsen B. Department of Biomedical Engineering, University of Trondheim, 7006, Trondheim, Norway aut NATIONALLICENCE 700 1- Rossvoll O. Department of Biomedical Engineering, University of Trondheim, 7006, Trondheim, Norway aut NATIONALLICENCE 700 1- Samstad S. Department of Biomedical Engineering, University of Trondheim, 7006, Trondheim, Norway aut NATIONALLICENCE 773 0- Medical and Biological Engineering and Computing Kluwer Academic Publishers 28/4(1990-07-01), 300-305 0140-0118 28:4<300 1990 28 11517 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer