caa a22 4500 465784666 CHVBK 20180323112004.0 cr unu---uuuuu 170327e19900301xx s 000 0 eng 10.1007/BF00811446 doi (NATIONALLICENCE)springer-10.1007/BF00811446 Nuclear medicine and atherosclerosis [Elektronische Daten] [Helmut Sinzinger, Irene Virgolini] Although the pathomechanisms of atherosclerosis are well known, their radioisotopic monitoring is still in its early childhood. The current radioisotope techniques are of only limited value for contributing to the clinical diagnosis of atherosclerosis. The limited reaction time of cellular blood constituents (platelets, monocytes) with the vascular surface at the injury site makes it very difficult to catch the point of injury. Lipoproteins excellently allow receptor imaging, while vascular monitoring is only of scientific interest at present. Labelling and subsequent imaging of components of the coagulation cascade have not succeeded so far, nor have attempts using unspecific labels such as porphyrin, polyclonal IgG and Fc fragments, for example. Preliminary evidence indicates that radioisotopic techniques may be of great benefit in the future in elucidating functional aspects of the disease, while they do not contribute to examining the stage and extent of atherosclerosis. Springer-Verlag, 1990 Atherosclerosis nationallicence Platelets nationallicence Monocytes nationallicence Low-density lipoproteins nationallicence Fibrinogen nationallicence Fibronectin nationallicence Porphyrin nationallicence Sinzinger Helmut Department of Nuclear Medicine, University of Vienna, Atherosclerosis Research Group of the Austrian Academy of Sciences and Atherosclerosis Research Group (ASF) Vienna, Schwarzspanierstrasse 17, A-1090, Vienna, Austria aut Virgolini Irene Department of Nuclear Medicine, University of Vienna, Atherosclerosis Research Group of the Austrian Academy of Sciences and Atherosclerosis Research Group (ASF) Vienna, Schwarzspanierstrasse 17, A-1090, Vienna, Austria aut European Journal of Nuclear Medicine Springer-Verlag 17/3-4(1990-03-01), 160-178 0340-6997 17:3-4<160 1990 17 259 https://doi.org/10.1007/BF00811446 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00811446 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sinzinger Helmut Department of Nuclear Medicine, University of Vienna, Atherosclerosis Research Group of the Austrian Academy of Sciences and Atherosclerosis Research Group (ASF) Vienna, Schwarzspanierstrasse 17, A-1090, Vienna, Austria aut NATIONALLICENCE 700 1- Virgolini Irene Department of Nuclear Medicine, University of Vienna, Atherosclerosis Research Group of the Austrian Academy of Sciences and Atherosclerosis Research Group (ASF) Vienna, Schwarzspanierstrasse 17, A-1090, Vienna, Austria aut NATIONALLICENCE 773 0- European Journal of Nuclear Medicine Springer-Verlag 17/3-4(1990-03-01), 160-178 0340-6997 17:3-4<160 1990 17 259 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer