caa a22 4500 465784763 CHVBK 20180323112005.0 cr unu---uuuuu 170327e19900301xx s 000 0 eng 10.1007/BF00811441 doi (NATIONALLICENCE)springer-10.1007/BF00811441 Scintigraphic study of gallbladder emptying and duodenogastric reflux during non-ulcerous dyspepsia [Elektronische Daten] [Jean-Pierre Caravel, Bruno Bonaz, Jean Hostein, Richard Bost, Jacques Fournet] Cholescintigraphy with technetium 99m hydroxy imino diacetic acid (99mTc-HIDA) was used to study gallbladder emptying (GE) and duodenogastric reflux (DGR) simultaneously during the postprandial period in humans. Two groups of subjects were examined prospectively; one was a group of healthy volunteers (n = 14) and the other a group of patients with nonulcerous dyspepsia (NUD) (n = 22). Symptoms were quantified using a clinical score (CS). GE kinetics was quantified according to two indices. DGR episodes were detected by an image-subtraction method and quantified. The group of patients with NUD showed significant early acceleration of GE (P > 0.01). One DGR episode equivalent to 1% of the injected dose was observed in 1 of the 14 control subjects, and >1% in 3 of the 22 NUD patients. However, there was no correlation between the CS, GE kinetics and DGR episodes. The physiopathological mechanism and clinical significance of these digestive motility anomalies remain to be demonstrated. springer-Verlag, 1990 Cholescintigraphy nationallicence Gallbladder emptying nationallicence Duodenogastric reflux nationallicence Non-ulcerous dyspepsia nationallicence Caravel Jean-Pierre Laboratoire d'Etudes des Radiopharmaceutiques URA CNRS 1287, Faculté de Médecine Grenoble, F-38700, La Tronche, France aut Bonaz Bruno Groupe de Recherche en Motricité Digestive, Service de Gastro-Enterologie et d'Hépatologie, Hôpital A. Michallon, CHRU, BP 217X, F-38043, Grenoble Cedex, France aut Hostein Jean Groupe de Recherche en Motricité Digestive, Service de Gastro-Enterologie et d'Hépatologie, Hôpital A. Michallon, CHRU, BP 217X, F-38043, Grenoble Cedex, France aut Bost Richard Groupe de Recherche en Motricité Digestive, Service de Gastro-Enterologie et d'Hépatologie, Hôpital A. Michallon, CHRU, BP 217X, F-38043, Grenoble Cedex, France aut Fournet Jacques Groupe de Recherche en Motricité Digestive, Service de Gastro-Enterologie et d'Hépatologie, Hôpital A. Michallon, CHRU, BP 217X, F-38043, Grenoble Cedex, France aut European Journal of Nuclear Medicine Springer-Verlag 17/3-4(1990-03-01), 134-141 0340-6997 17:3-4<134 1990 17 259 https://doi.org/10.1007/BF00811441 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00811441 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Caravel Jean-Pierre Laboratoire d'Etudes des Radiopharmaceutiques URA CNRS 1287, Faculté de Médecine Grenoble, F-38700, La Tronche, France aut NATIONALLICENCE 700 1- Bonaz Bruno Groupe de Recherche en Motricité Digestive, Service de Gastro-Enterologie et d'Hépatologie, Hôpital A. Michallon, CHRU, BP 217X, F-38043, Grenoble Cedex, France aut NATIONALLICENCE 700 1- Hostein Jean Groupe de Recherche en Motricité Digestive, Service de Gastro-Enterologie et d'Hépatologie, Hôpital A. Michallon, CHRU, BP 217X, F-38043, Grenoble Cedex, France aut NATIONALLICENCE 700 1- Bost Richard Groupe de Recherche en Motricité Digestive, Service de Gastro-Enterologie et d'Hépatologie, Hôpital A. Michallon, CHRU, BP 217X, F-38043, Grenoble Cedex, France aut NATIONALLICENCE 700 1- Fournet Jacques Groupe de Recherche en Motricité Digestive, Service de Gastro-Enterologie et d'Hépatologie, Hôpital A. Michallon, CHRU, BP 217X, F-38043, Grenoble Cedex, France aut NATIONALLICENCE 773 0- European Journal of Nuclear Medicine Springer-Verlag 17/3-4(1990-03-01), 134-141 0340-6997 17:3-4<134 1990 17 259 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer