caa a22 4500 465785166 CHVBK 20180323112007.0 cr unu---uuuuu 170327e19900601xx s 000 0 eng 10.1007/BF01268023 doi (NATIONALLICENCE)springer-10.1007/BF01268023 Estimation of pulmonary hypertension by perfusion lung scintigraphy: gravitational effect of postural changes between the lateral decubitus positions [Elektronische Daten] [Masao Tanaka, Tadashige Fujii, Jiro Hirayama, Shinichi Okubo, Morie Sekiguchi] To estimate pulmonary hypertension in patients with various heart diseases, we devised a new method using perfuison lung scintigraphy with technetium-99m-labelled macroaggregated albumin. In this method, changes in the distribution of pulmonary perfusion caused by gravitational effects, namely, changes in the total count ratios of the right lung against the left lung between right and left lateral decubitus positions (rt/lt), were assessed in 62 patients and in 10 normal subjects. The rt/lt ratios were calculated as indices of the above changes. They correlated significantly with mean pulmonary arterial pressure (mPAP) (γ= −0.62,P < 0.001), pulmonary capillary wedge pressure (γ = −0.63,P < 0.001) and pulmonary arteriolar resistance (γ = 0.50,P < 0.001) in all subjects. In 17 patients with valvular heart diseases, the ratio correlated significantly with mPAP (γ = − 0.84,P < 0.001). In 10 patients with various heart diseases, the U/S ratio, i.e. the index of changes in the count ratios of the upper field against the lower field for the right lung following postural change from the upright to the supine position, was also obtained as well as the rt/lt ratio. The latter evidenced a better correlation with mPAP (γ = −0.90,P < 0.001) than the former (γ=−0.64,P < 0.05). We conclude that this method is valuable as a noninvasive approach for the estimation of pulmonary hypertension. Springer-Verlag, 1990 Pulmonary hypertension nationallicence Postural changes nationallicence Left and right lateral decubitus positions nationallicence Perfusion lung scintigraphy nationallicence Gravitational effect nationallicence Tanaka Masao First Department of Internal Medicine, Shinshu University School of Medicine, 3-1-1 Asahi, 390, Matsumoto, Japan aut Fujii Tadashige First Department of Internal Medicine, Shinshu University School of Medicine, 3-1-1 Asahi, 390, Matsumoto, Japan aut Hirayama Jiro First Department of Internal Medicine, Shinshu University School of Medicine, 3-1-1 Asahi, 390, Matsumoto, Japan aut Okubo Shinichi First Department of Internal Medicine, Shinshu University School of Medicine, 3-1-1 Asahi, 390, Matsumoto, Japan aut Sekiguchi Morie First Department of Internal Medicine, Shinshu University School of Medicine, 3-1-1 Asahi, 390, Matsumoto, Japan aut European Journal of Nuclear Medicine Springer-Verlag 17/6-8(1990-06-01), 320-326 0340-6997 17:6-8<320 1990 17 259 https://doi.org/10.1007/BF01268023 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01268023 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Tanaka Masao First Department of Internal Medicine, Shinshu University School of Medicine, 3-1-1 Asahi, 390, Matsumoto, Japan aut NATIONALLICENCE 700 1- Fujii Tadashige First Department of Internal Medicine, Shinshu University School of Medicine, 3-1-1 Asahi, 390, Matsumoto, Japan aut NATIONALLICENCE 700 1- Hirayama Jiro First Department of Internal Medicine, Shinshu University School of Medicine, 3-1-1 Asahi, 390, Matsumoto, Japan aut NATIONALLICENCE 700 1- Okubo Shinichi First Department of Internal Medicine, Shinshu University School of Medicine, 3-1-1 Asahi, 390, Matsumoto, Japan aut NATIONALLICENCE 700 1- Sekiguchi Morie First Department of Internal Medicine, Shinshu University School of Medicine, 3-1-1 Asahi, 390, Matsumoto, Japan aut NATIONALLICENCE 773 0- European Journal of Nuclear Medicine Springer-Verlag 17/6-8(1990-06-01), 320-326 0340-6997 17:6-8<320 1990 17 259 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer