caa a22 4500 465785204 CHVBK 20180323112007.0 cr unu---uuuuu 170327e19900601xx s 000 0 eng 10.1007/BF01268021 doi (NATIONALLICENCE)springer-10.1007/BF01268021 Simultaneous measurement of left ventricular function and perfusion [Elektronische Daten] [A. Elliott, J. McKillop, S. Pringle, G. Gillen, J. Wilson, A. Lorimer, H. Dargie] A new radiopharmaceutical, methylisobutyl isonitrile (MIBI), has been developed as a technetium 99m-labelled alternative to thallium 201 for myocardial imaging. By virtue of the high specific activity of99mTc, some 600 MBq may be administered as a 0.3 ml bolus, permitting the acquisition of a first-pass nuclear angiogram at rest and at peak exercise. The agent was assessed in ten sequential patients referred for routine cardiac catheterisation, who also underwent an exercise electrocardiographic (ECG) test. Good quality nuclear angiograms, planar perfusion and tomographic perfusion im ages were obtained; the results correlated well with the catheterisation data. Of 30 myocardial segments for which wall motion was judged normal/abnormal from the nuclear angiogram, results concordant with contrast studies were obtained in 27 (90%). In the case of the 50 segments analysed from the perfusion images, concordant results were obtained in 43 (86%) from the planar studies and in 42 (84%) from the tomographic studies. All normal segments were classified correctly. Springer-Verlag, 1990 Myocardial perfusion imaging nationallicence Left ventricular function nationallicence Methylisobutyl isonitrile (MIBI) nationallicence Single photon emisssion computed tomography (SPET) nationallicence Elliott A. Department of Clinical Physics and Bioengineering, Western Infirmary, G11, 6NT, Glasgow, UK aut McKillop J. University Department of Medicine, Royal Infirmary, G31 2ER, Glasgow, UK aut Pringle S. Department of Medical Cardiology, Royal Infirmary, G31 2ER, Glasgow, UK aut Gillen G. Department of Clinical Physics and Bioengineering, Western Infirmary, G11, 6NT, Glasgow, UK aut Wilson J. Department of Clinical Physics and Bioengineering, Western Infirmary, G11, 6NT, Glasgow, UK aut Lorimer A. Department of Medical Cardiology, Royal Infirmary, G31 2ER, Glasgow, UK aut Dargie H. Department of Cardiology, Western Infirmary, G11, 6NT, Glasgow, UK aut European Journal of Nuclear Medicine Springer-Verlag 17/6-8(1990-06-01), 310-314 0340-6997 17:6-8<310 1990 17 259 https://doi.org/10.1007/BF01268021 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01268021 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Elliott A. Department of Clinical Physics and Bioengineering, Western Infirmary, G11, 6NT, Glasgow, UK aut NATIONALLICENCE 700 1- McKillop J. University Department of Medicine, Royal Infirmary, G31 2ER, Glasgow, UK aut NATIONALLICENCE 700 1- Pringle S. Department of Medical Cardiology, Royal Infirmary, G31 2ER, Glasgow, UK aut NATIONALLICENCE 700 1- Gillen G. Department of Clinical Physics and Bioengineering, Western Infirmary, G11, 6NT, Glasgow, UK aut NATIONALLICENCE 700 1- Wilson J. Department of Clinical Physics and Bioengineering, Western Infirmary, G11, 6NT, Glasgow, UK aut NATIONALLICENCE 700 1- Lorimer A. Department of Medical Cardiology, Royal Infirmary, G31 2ER, Glasgow, UK aut NATIONALLICENCE 700 1- Dargie H. Department of Cardiology, Western Infirmary, G11, 6NT, Glasgow, UK aut NATIONALLICENCE 773 0- European Journal of Nuclear Medicine Springer-Verlag 17/6-8(1990-06-01), 310-314 0340-6997 17:6-8<310 1990 17 259 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer