caa a22 4500 465785328 CHVBK 20180323112007.0 cr unu---uuuuu 170327e19900501xx s 000 0 eng 10.1007/BF00812365 doi (NATIONALLICENCE)springer-10.1007/BF00812365 SPET brain imaging with 201 diethyldithiocarbamate in acute ischaemic stroke [Elektronische Daten] [J. de Bruïne, Martien Limburg, Eric van Royen, Albert Hijdra, Thomas Hill, Jan van der Schoot] Thirty-five patients with acute ischaemic stroke were studied within 24 h after hospital admission with thallium 201 diethyldithiocarbamate single photon emission tomography (201TI-DDC SPET) and X-ray computed tomography (CT).201TI-DDC is a non-redistributing agent that allows postponed imaging after early administration and early therapeutic intervention. In 16 patients both investigations were performed within 24 h after stroke onset. The sensitivity of SPET was 94% and of CT 81 % in the first 24 h, when hypodensity and obliteration of sulci were used as CT reading criteria. When only hypodensity was used as a criterion, the sensitivity of CT was 50% in this group. Sensitivity of CT compared with SPET became increasingly better in patients with older infarcts (1-18 days). In two-thirds of patients, the lesion demonstrated on SPET was larger than that on CT, and this was especially so with older infarcts. Crossed cerebellar diaschisis occurred in 69% of patients. The high sensitivity of201TI-DDC SPET in the first 24 h after ischaemic stroke and the favourable properties of this radiopharmaceutical make it a method of interest in the assessment of initial perfusion defects in early experimental stroke therapies. Springer-Verlag, 1990 Emission computed tomography nationallicence Cerebral infarction nationallicence Thallium 201 diethyldithiocarbamate nationallicence Sensitivity nationallicence Diaschisis nationallicence de Bruïne J. Department of Nuclear Medicine, Academisch Medisch Centrum, Meibergdreef 9, NL-1105 AZ, Amsterdam, The Netherlands aut Limburg Martien Department of Neurology, Academisch Medisch Centrum, Meibergdreef 9, NL-1105 AZ, Amsterdam, The Netherlands aut van Royen Eric Department of Nuclear Medicine, Academisch Medisch Centrum, Meibergdreef 9, NL-1105 AZ, Amsterdam, The Netherlands aut Hijdra Albert Department of Neurology, Academisch Medisch Centrum, Meibergdreef 9, NL-1105 AZ, Amsterdam, The Netherlands aut Hill Thomas Department of Nuclear Medicine, New England Deaconess Hospital, Harvard Medical School, 02181, Boston, MA, USA aut van der Schoot Jan Department of Nuclear Medicine, Academisch Medisch Centrum, Meibergdreef 9, NL-1105 AZ, Amsterdam, The Netherlands aut European Journal of Nuclear Medicine Springer-Verlag 17/5(1990-05-01), 248-251 0340-6997 17:5<248 1990 17 259 https://doi.org/10.1007/BF00812365 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00812365 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- de Bruïne J. Department of Nuclear Medicine, Academisch Medisch Centrum, Meibergdreef 9, NL-1105 AZ, Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- Limburg Martien Department of Neurology, Academisch Medisch Centrum, Meibergdreef 9, NL-1105 AZ, Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- van Royen Eric Department of Nuclear Medicine, Academisch Medisch Centrum, Meibergdreef 9, NL-1105 AZ, Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- Hijdra Albert Department of Neurology, Academisch Medisch Centrum, Meibergdreef 9, NL-1105 AZ, Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- Hill Thomas Department of Nuclear Medicine, New England Deaconess Hospital, Harvard Medical School, 02181, Boston, MA, USA aut NATIONALLICENCE 700 1- van der Schoot Jan Department of Nuclear Medicine, Academisch Medisch Centrum, Meibergdreef 9, NL-1105 AZ, Amsterdam, The Netherlands aut NATIONALLICENCE 773 0- European Journal of Nuclear Medicine Springer-Verlag 17/5(1990-05-01), 248-251 0340-6997 17:5<248 1990 17 259 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer