caa a22 4500 465785344 CHVBK 20180323112007.0 cr unu---uuuuu 170327e19900501xx s 000 0 eng 10.1007/BF00812366 doi (NATIONALLICENCE)springer-10.1007/BF00812366 Abnormal septal motion after aortic valve replacement for chronic aortic regurgitation: no evidence for myocardial ischaemia by exercise radionuclide angiography [Elektronische Daten] [Ernst van der Wall, Manufris Kasim, Jan Camps, Gerda van Rijk-Zwikker, Paul Voogd, Ernest Pauwels, Albert Bruschke] To evaluate interventricular septal motion and left ventricular function after aortic valve replacement for chronic aortic regurgitation, we studied 12 patients at rest and during exercise by radionuclide angiography after a mean of 19 (range 12-36) months after operation (group I). Twenty patients with chronic aortic regurgitation without aortic valve replacement served as controls (group II). None of the patients had coronary artery disease as documented by arteriography. Abnormal interventricular septal motion at rest was seen in 11 patients of group I, of whom 8 showed hypokinesis and 3 akinesis. During exercise, the interventricular septal wall motion improved in 4 patients, worsened in 3 patients and did not change in 5 patients. All patients of group II had normal interventricular septal motion at rest. During exercise, 5 patients showed septal wall hypokinesia together with apical and posterolateral wall motion abnormalities. The left ventricular ejection fraction at rest was 62% ± 20% in group I and 66% ± 8% in group II (not significant). During exercise, the left ventricular ejection fraction was 59% ± 24% in group I and 68% ±13% in group II (not significant). We conclude that abnormal interventricular septal motion at rest is commonly found in patients with aortic valve replacement for chronic aortic regurgitation. During exercise, septal wall motion in the patients with aortic valve replacement shows a variable response from complete normalization to akinesia. These findings are mostly associated with a normal global left ventricular function both at rest and during exercise, which precludes myocardial ischaemia as a primary cause for abnormal septal wall motion after aortic valve replacement. Springer-Verlag, 1990 Radionuclide angiography nationallicence Exercise nationallicence Aortic valve replacement nationallicence Aortic valve insufficiency nationallicence Septal wall motion nationallicence van der Wall Ernst Department of Cardiology, University Hospital Leiden, Rijnsburgerweg 10, NL-2333 AA, Leiden, The Netherlands aut Kasim Manufris Department of Cardiology, University Hospital Leiden, Rijnsburgerweg 10, NL-2333 AA, Leiden, The Netherlands aut Camps Jan Department of Nuclear Medicine, University Hospital Leiden, Rijnsburgerweg 10, NL-2333 AA, Leiden, The Netherlands aut van Rijk-Zwikker Gerda Department of Cardiovascular Surgery, University Hospital Leiden, Rijnsburgerweg 10, NL-2333 AA, Leiden, The Netherlands aut Voogd Paul Department of Cardiology, University Hospital Leiden, Rijnsburgerweg 10, NL-2333 AA, Leiden, The Netherlands aut Pauwels Ernest Department of Nuclear Medicine, University Hospital Leiden, Rijnsburgerweg 10, NL-2333 AA, Leiden, The Netherlands aut Bruschke Albert Department of Cardiology, University Hospital Leiden, Rijnsburgerweg 10, NL-2333 AA, Leiden, The Netherlands aut European Journal of Nuclear Medicine Springer-Verlag 17/5(1990-05-01), 252-256 0340-6997 17:5<252 1990 17 259 https://doi.org/10.1007/BF00812366 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00812366 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- van der Wall Ernst Department of Cardiology, University Hospital Leiden, Rijnsburgerweg 10, NL-2333 AA, Leiden, The Netherlands aut NATIONALLICENCE 700 1- Kasim Manufris Department of Cardiology, University Hospital Leiden, Rijnsburgerweg 10, NL-2333 AA, Leiden, The Netherlands aut NATIONALLICENCE 700 1- Camps Jan Department of Nuclear Medicine, University Hospital Leiden, Rijnsburgerweg 10, NL-2333 AA, Leiden, The Netherlands aut NATIONALLICENCE 700 1- van Rijk-Zwikker Gerda Department of Cardiovascular Surgery, University Hospital Leiden, Rijnsburgerweg 10, NL-2333 AA, Leiden, The Netherlands aut NATIONALLICENCE 700 1- Voogd Paul Department of Cardiology, University Hospital Leiden, Rijnsburgerweg 10, NL-2333 AA, Leiden, The Netherlands aut NATIONALLICENCE 700 1- Pauwels Ernest Department of Nuclear Medicine, University Hospital Leiden, Rijnsburgerweg 10, NL-2333 AA, Leiden, The Netherlands aut NATIONALLICENCE 700 1- Bruschke Albert Department of Cardiology, University Hospital Leiden, Rijnsburgerweg 10, NL-2333 AA, Leiden, The Netherlands aut NATIONALLICENCE 773 0- European Journal of Nuclear Medicine Springer-Verlag 17/5(1990-05-01), 252-256 0340-6997 17:5<252 1990 17 259 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer