caa a22 4500 46578593X CHVBK 20180323112009.0 cr unu---uuuuu 170327e19900401xx s 000 0 eng 10.1007/BF00842781 doi (NATIONALLICENCE)springer-10.1007/BF00842781 Single photon emission computed tomography (SPELT) using N-isopropyl-p-(123I)iodoamphetamine (IMP) in the evaluation of patients with epileptic seizures [Elektronische Daten] [Masashi Kawamura, Kenya Murase, Hideki Kimura, Takao Hatakeyama, Hiroshi Mogami, Masaaki Kataoka, Hisao Itoh, Masahiro Ishine, Atsushi Iio, Ken Hamamoto, Saburo Sakaki, Kenzo Matsuoka] To evaluate the clinical usefulness of IMP SPECT in the diagnosis of epilepsy, 6 normals and 52 patients in the interictal phase were studied. Thirty min after an intravenous injection of 111 MBq IMP, SPECT was performed using a rotating gamma camera. Of 21 patients with simple partial seizures, a localized decrease of uptake was shown in 16, and an increase in 3. Topologically, these findings corresponded well to the ictal symptoms. Nine of 13 patients with localized epileptic EEG had a good correspondence between the findings on EEG and IMP SPELT. In 20 of 23 with complex partial seizures, the coronal images showed laterality of uptake in the temporal lobes, whereas the CT was normal in 14. However, these findings on IMP SPECT agreed with the EEG in the temporal leads in only 5 cases. Of 8 patients with primary generalized seizures, a diffuse cerebral decrease was shown in 3 of 4 patients with convulsive seizures (grand mal), and a normal uptake in 3 of 4 patients with non-convulsive seizures (petit mal). However, 2 patients showed a localized decrease, therefore, we determined that they suffered from partial seizures evolving to secondarily generalization. From these data, we concluded that IMP SPELT could be a useful method in the diagnosis of epilepsy. Springer-Verlag, 1990 Brain imaging nationallicence Epilepsy nationallicence 123I-IMP nationallicence SPECT nationallicence Kawamura Masashi Department of Radiology, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, Onsen-gun, 791-02, Ehime, Japan aut Murase Kenya Department of Radiology, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, Onsen-gun, 791-02, Ehime, Japan aut Kimura Hideki Department of Neurosurgery, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, Onsen-gun, 791-02, Ehime, Japan aut Hatakeyama Takao Department of Neurosurgery, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, Onsen-gun, 791-02, Ehime, Japan aut Mogami Hiroshi Department of Radiology, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, Onsen-gun, 791-02, Ehime, Japan aut Kataoka Masaaki Department of Radiology, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, Onsen-gun, 791-02, Ehime, Japan aut Itoh Hisao Department of Radiology, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, Onsen-gun, 791-02, Ehime, Japan aut Ishine Masahiro Department of Radiology, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, Onsen-gun, 791-02, Ehime, Japan aut Iio Atsushi Department of Radiology, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, Onsen-gun, 791-02, Ehime, Japan aut Hamamoto Ken Department of Radiology, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, Onsen-gun, 791-02, Ehime, Japan aut Sakaki Saburo Department of Radiology, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, Onsen-gun, 791-02, Ehime, Japan aut Matsuoka Kenzo Department of Neurosurgery, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, Onsen-gun, 791-02, Ehime, Japan aut European Journal of Nuclear Medicine Springer-Verlag 16/4-6(1990-04-01), 285-292 0340-6997 16:4-6<285 1990 16 259 https://doi.org/10.1007/BF00842781 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00842781 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kawamura Masashi Department of Radiology, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, Onsen-gun, 791-02, Ehime, Japan aut NATIONALLICENCE 700 1- Murase Kenya Department of Radiology, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, Onsen-gun, 791-02, Ehime, Japan aut NATIONALLICENCE 700 1- Kimura Hideki Department of Neurosurgery, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, Onsen-gun, 791-02, Ehime, Japan aut NATIONALLICENCE 700 1- Hatakeyama Takao Department of Neurosurgery, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, Onsen-gun, 791-02, Ehime, Japan aut NATIONALLICENCE 700 1- Mogami Hiroshi Department of Radiology, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, Onsen-gun, 791-02, Ehime, Japan aut NATIONALLICENCE 700 1- Kataoka Masaaki Department of Radiology, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, Onsen-gun, 791-02, Ehime, Japan aut NATIONALLICENCE 700 1- Itoh Hisao Department of Radiology, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, Onsen-gun, 791-02, Ehime, Japan aut NATIONALLICENCE 700 1- Ishine Masahiro Department of Radiology, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, Onsen-gun, 791-02, Ehime, Japan aut NATIONALLICENCE 700 1- Iio Atsushi Department of Radiology, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, Onsen-gun, 791-02, Ehime, Japan aut NATIONALLICENCE 700 1- Hamamoto Ken Department of Radiology, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, Onsen-gun, 791-02, Ehime, Japan aut NATIONALLICENCE 700 1- Sakaki Saburo Department of Radiology, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, Onsen-gun, 791-02, Ehime, Japan aut NATIONALLICENCE 700 1- Matsuoka Kenzo Department of Neurosurgery, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, Onsen-gun, 791-02, Ehime, Japan aut NATIONALLICENCE 773 0- European Journal of Nuclear Medicine Springer-Verlag 16/4-6(1990-04-01), 285-292 0340-6997 16:4-6<285 1990 16 259 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer