caa a22 4500 465785948 CHVBK 20180323112009.0 cr unu---uuuuu 170327e19900401xx s 000 0 eng 10.1007/BF00842771 doi (NATIONALLICENCE)springer-10.1007/BF00842771 Mannting Finn Department of Clinical Physiology, Nuclear Medicine Section, University Hospital, S-751 85, Uppsala, Sweden aut A new method for quantification of pulmonary thallium uptake in myocardial SPECT studies [Elektronische Daten] [Finn Mannting] Quantified pulmonary thallium 201 (TI) uptake was assessed in 32 normal subjects and 66 patients with suspected coronary artery disease (CAD) by a new method utilizing SPECT acquisition data. In 26 subjects pulmonary uptake was assessed with both SPECT and planar techniques. Pulmonary/myocardial (PM) ratios for the whole right lung (PM1) and for the upper left lung (PM2) were computed and compared with stress test, coronary angiography, radionuclide angiography (ERNA), and quantified TI single photon emission computed tomography (SPECT) results. Excellent correlation between pulmonary uptake assessed by planar and SPECT technique was disclosed (r=0.92). The PM ratios (PM1/PM2) sensitivity and specificity in patients with CAD were 88%/92% and 60%/70%, for predicting perfusion abnormalities 90%/87% and 88%/88%, and an inverse correlation to left ventricular ejection fraction (LVEF) was found (r=−0.40/r=−0.37,P<0.01). Significant correlations to coronary angiography findings (r=0.54/r=0.49,P<0.001) and to number of vessel territories with abnormal perfusion (r=0.70/r=0.69,P< 0.001) were seen. Thus, pulmonary TI uptake can be assessed in SPECT studies. The new method's discriminative ability seems higher than that of the standard planar techniques currently employed. Positive correlations to coronary angiography findings and even stronger ones to perfusion abnormalities were observed. Springer-Verlag, 1990 Lung thallium uptake nationallicence Thallium SPECT nationallicence Left ventricular failure nationallicence Coronary artery disease nationallicence European Journal of Nuclear Medicine Springer-Verlag 16/4-6(1990-04-01), 213-222 0340-6997 16:4-6<213 1990 16 259 https://doi.org/10.1007/BF00842771 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00842771 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Mannting Finn Department of Clinical Physiology, Nuclear Medicine Section, University Hospital, S-751 85, Uppsala, Sweden aut NATIONALLICENCE 773 0- European Journal of Nuclear Medicine Springer-Verlag 16/4-6(1990-04-01), 213-222 0340-6997 16:4-6<213 1990 16 259 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer