caa a22 4500 465786065 CHVBK 20180323112009.0 cr unu---uuuuu 170327e19900801xx s 000 0 eng 10.1007/BF00998180 doi (NATIONALLICENCE)springer-10.1007/BF00998180 Nicoietti Rudolf Department of Radiology, Division for Nuclear Medicine, Karl-Franzens-University, Auenbruggerplatz, A-8036, Graz, Austria aut Evaluation of renal transplant perfusion by functional imaging [Elektronische Daten] [Rudolf Nicoietti] Radionuclide angiography (RNA) is used as a noninvasive method for the evaluation of renal transplant perfusion. The computer processing method generally used, based on regions of interest, is unsatisfactory because it does not permit the regional differentiation of perfusion defects. Furthermore, the subjective delineation of the regions of interest introduces considerable inter-observer variation of results. We developed a processing method which is less operator-dependent and permits the evaluation of local defects; it is based on the concept of functional imaging. The method was evaluated in 62 patient examinations, which were subdivided into four groups: normal transplant perfusion (23 examinations), acute tubular necrosis (ATN) (16), cellular rejection (13), and vascular rejection (10). Quantitative results derived from profile curves were combined with visual estimation of the functional images and yielded a synoptic graph which allowed differentiation into three groups: normal transplant perfusion (sensitivity 0.78, specificity 0.97), ATN or cellular rejection (sens. 0.83, spec. 0.82), and vascular rejection (sens. 0.90, spec. 0.92). Springer-Verlag, 1990 Functional imaging nationallicence Renal transplant perfusion nationallicence Perfusion index nationallicence First pass method nationallicence European Journal of Nuclear Medicine Springer-Verlag 16/8-10(1990-08-01), 733-739 0340-6997 16:8-10<733 1990 16 259 https://doi.org/10.1007/BF00998180 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00998180 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Nicoietti Rudolf Department of Radiology, Division for Nuclear Medicine, Karl-Franzens-University, Auenbruggerplatz, A-8036, Graz, Austria aut NATIONALLICENCE 773 0- European Journal of Nuclear Medicine Springer-Verlag 16/8-10(1990-08-01), 733-739 0340-6997 16:8-10<733 1990 16 259 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer