caa a22 4500 46578609X CHVBK 20180323112009.0 cr unu---uuuuu 170327e19900801xx s 000 0 eng 10.1007/BF00998157 doi (NATIONALLICENCE)springer-10.1007/BF00998157 Parathyroid imaging by Tc/TI scintigraphy [Elektronische Daten] [Dirk Sandrock, Maria Merino, Jeffrey Norton, Ronald Neumann] Between 1983 and 1988, a total of 22499mTc/201T1 subtraction parathyroid scintigraphy studies were performed in 214 patients (136 women, 78 men, average age 50, ±15 years) with clinical and biochemical signs of hyperparathyroidism. Of the 214 patients, 113 underwent surgical exploration, and 127 benign parathyroid lesions were found, 48 of which were correctly localized by scintigraphy (sensitivity 38%). We detected 30 of 71 adenomas (42%) and 18 of 56 hyperplastic glands (32%). Additionally, the scans localized 2 of 6 parathyroid carcinomas in 5 patients. Overall, 83 parathyroid lesions were missed. There was no significant difference in size between detected and missed lesions. Previous neck surgery (65 of 113 patients) was not a significant detriment to scan sensitivity; but correct detection did depend upon the anatomic site of the lesion: 39% (n=109) were detected in the typical site, 44% (n=9) intrathyroidal, and 11 % (n=9) in the anterior and/or superior mediastinum. In conclusion, these results show only limited value for this99mTc/201T1 subtraction scintigraphy protocol as the initial procedure for localization of abnormal parathyroid tissue prior to surgical exploration. Springer-Verlag, 1990 Radionuclide imaging nationallicence Parathyroid, hyperparathyroidism nationallicence Parathyroid, neoplasms nationallicence Sandrock Dirk Department of Nuclear Medicine, Warren G. Magnuson Clinical Center, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA aut Merino Maria Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA aut Norton Jeffrey Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA aut Neumann Ronald Department of Nuclear Medicine, Warren G. Magnuson Clinical Center, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA aut European Journal of Nuclear Medicine Springer-Verlag 16/8-10(1990-08-01), 607-613 0340-6997 16:8-10<607 1990 16 259 https://doi.org/10.1007/BF00998157 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00998157 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sandrock Dirk Department of Nuclear Medicine, Warren G. Magnuson Clinical Center, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA aut NATIONALLICENCE 700 1- Merino Maria Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA aut NATIONALLICENCE 700 1- Norton Jeffrey Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA aut NATIONALLICENCE 700 1- Neumann Ronald Department of Nuclear Medicine, Warren G. Magnuson Clinical Center, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA aut NATIONALLICENCE 773 0- European Journal of Nuclear Medicine Springer-Verlag 16/8-10(1990-08-01), 607-613 0340-6997 16:8-10<607 1990 16 259 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer