caa a22 4500 46578612X CHVBK 20180323112009.0 cr unu---uuuuu 170327e19900801xx s 000 0 eng 10.1007/BF00998167 doi (NATIONALLICENCE)springer-10.1007/BF00998167 Dynamic quantitative bone scintigraphy in patients with prostatic carcinoma treated by orchiectomy [Elektronische Daten] [Gunilla Sundkvist, Lars Ahlgren, Bo Lilja, Sören Mattsson, Per-Anders Abrahamsson] Dynamic quantitative bone scintigraphy was performed on 31 men with prostatic carcinoma before orchiectomy as well as 2 weeks, 2 and 6 months post-operatively. After injection of technetium methylene diphosphonate Tc 99m (99mTc-MDP) the count rate was recorded as serial images over the lower thoracic and all the lumbar vertebrae from 1 to 240 min post-injection. Thirteen men had normal bone scintigrams with no changes in99mTc-MDP content at the four different investigation times. Eighteen men had skeletal metastases. Throughout the study half of the abnormal vertebrae in these patients showed an abnormal count rate after only 6 min post-injection. After 1 h it was possible in almost all abnormal vertebrae to predict abnormal bone uptake. In response to therapy a "flare phenomenon” with an increase in count rate was seen 2 weeks after orchiectomy followed by a decrease 2 months post-operatively in most of the abnormal vertebrae. The count rate decreased even below the pre-operative level after 6 months. Also, the normal vertebrae in the patients with skeletal metastases showed a tendency towards the flare phenomenon, which was not seen in patients with normal bone scintigrams. Springer-Verlag, 1990 Dynamic quantitative bone scintigraphy nationallicence Prostatic carcinoma nationallicence Skeletal metastases nationallicence Orchiectomy nationallicence Flare phenomenon nationallicence Sundkvist Gunilla Department of Clinical Physiology, Lund University, Malmö General Hospital, S-21401, Malmö, Sweden aut Ahlgren Lars Department of Radiation Physics, Lund University, Malmö General Hospital, S-21401, Malmö, Sweden aut Lilja Bo Department of Clinical Physiology, Lund University, Malmö General Hospital, S-21401, Malmö, Sweden aut Mattsson Sören Department of Radiation Physics, Lund University, Malmö General Hospital, S-21401, Malmö, Sweden aut Abrahamsson Per-Anders Department of Urology, Lund University, Malmö General Hospital, S-21401, Malmö, Sweden aut European Journal of Nuclear Medicine Springer-Verlag 16/8-10(1990-08-01), 671-676 0340-6997 16:8-10<671 1990 16 259 https://doi.org/10.1007/BF00998167 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00998167 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sundkvist Gunilla Department of Clinical Physiology, Lund University, Malmö General Hospital, S-21401, Malmö, Sweden aut NATIONALLICENCE 700 1- Ahlgren Lars Department of Radiation Physics, Lund University, Malmö General Hospital, S-21401, Malmö, Sweden aut NATIONALLICENCE 700 1- Lilja Bo Department of Clinical Physiology, Lund University, Malmö General Hospital, S-21401, Malmö, Sweden aut NATIONALLICENCE 700 1- Mattsson Sören Department of Radiation Physics, Lund University, Malmö General Hospital, S-21401, Malmö, Sweden aut NATIONALLICENCE 700 1- Abrahamsson Per-Anders Department of Urology, Lund University, Malmö General Hospital, S-21401, Malmö, Sweden aut NATIONALLICENCE 773 0- European Journal of Nuclear Medicine Springer-Verlag 16/8-10(1990-08-01), 671-676 0340-6997 16:8-10<671 1990 16 259 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer