caa a22 4500 465786138 CHVBK 20180323112009.0 cr unu---uuuuu 170327e19900801xx s 000 0 eng 10.1007/BF00998172 doi (NATIONALLICENCE)springer-10.1007/BF00998172 Is quantitative analysis superior to visual analysis of planar thallium 201 myocardial exercise scintigraphy in the evaluation of coronary artery disease? [Elektronische Daten] Analysis of a prospective clinical study [Menco Niemeyer, Gerrit Laarman, Ernst van der Wall, Maarten Cramer, Fred Verzijlbergen, Aelko Zwindermans, Carl Ascoop, Ernest Pauwels] Quantitative analysis of myocardial exercise scintigraphy has been previously reported to be superior to visual image interpretation for detection of the presence and extent of coronary artery disease. Computer analysis of perfusion defects and washout rate of thallium 201 was performed on scintigrams from a group of 131 consecutive patients (prospective group), using criteria defined from a previous group of 72 patients (initial group), and compared with visual interpretation of scintigrams for detection and evaluation of coronary artery disease. The sensitivity of the quantitative technique with regard to overall detection of coronary artery disease was not significantly different from the visual method (69% and 74%, respectively), whereas the specificity was higher (86% and 68%). Quantitative analysis did not increase the sensitivity of thallium imaging over the visual method in the left anterior descending artery (46% vs 65%) and the right coronary artery (51% vs 72%) but did increase sensitivity in the left circumflex artery (75% vs 47%). Whereas in the initial group quantitative analysis resulted in a better identification of multivessel disease (sensitivity 81 % vs 57%), in the prospective group sensitivity decreased (54% vs 67%) without significant loss of specificity. The initial group had a 40% incidence of three-vessel disease and the prospective group, 22% (P < 0.05). One-vessel disease was higher in the prospective group (32% vs 11%,P < 0.05). Thus, assessing the quantitative technique in a larger prospective patient population, there was no improvement of detection of the presence and extent of coronary artery disease when compared with visual interpretation. Springer-Verlag, 1990 Thallium 201 myocardial scintigraphy nationallicence Thallium 201 washout nationallicence Exercise test nationallicence Coronary artery disease nationallicence Niemeyer Menco Department of Diagnostic Radiology, University Hospital, Rijnsburgerweg 10, 2333 AA, Leiden, The Netherlands aut Laarman Gerrit Department of Cardiology, Thorax Center, University Hospital, Bd 414, PO Box 1738, 3000 DR, Rotterdam, The Netherlands aut van der Wall Ernst Department of Cardiology, University Hospital, Rijnsburgerweg 10, 2333 AA, Leiden, The Netherlands aut Cramer Maarten Department of Cardiology, St Antonius Hospital, Koekoekslaan 1, 3435 CM, Nieuwegein, The Netherlands aut Verzijlbergen Fred Department of Nuclear Cardiology, St Antonius Hospital, Koekoekslaan 1, 3435 CM, Nieuwegein, The Netherlands aut Zwindermans Aelko Department of Medical Statistics, University of Leiden, Niels Bohrweg 1, 2333 CL, Leiden, The Netherlands aut Ascoop Carl Department of Cardiology, St Antonius Hospital, Koekoekslaan 1, 3435 CM, Nieuwegein, The Netherlands aut Pauwels Ernest Department of Diagnostic Radiology, University Hospital, Rijnsburgerweg 10, 2333 AA, Leiden, The Netherlands aut European Journal of Nuclear Medicine Springer-Verlag 16/8-10(1990-08-01), 697-704 0340-6997 16:8-10<697 1990 16 259 https://doi.org/10.1007/BF00998172 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00998172 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Niemeyer Menco Department of Diagnostic Radiology, University Hospital, Rijnsburgerweg 10, 2333 AA, Leiden, The Netherlands aut NATIONALLICENCE 700 1- Laarman Gerrit Department of Cardiology, Thorax Center, University Hospital, Bd 414, PO Box 1738, 3000 DR, Rotterdam, The Netherlands aut NATIONALLICENCE 700 1- van der Wall Ernst Department of Cardiology, University Hospital, Rijnsburgerweg 10, 2333 AA, Leiden, The Netherlands aut NATIONALLICENCE 700 1- Cramer Maarten Department of Cardiology, St Antonius Hospital, Koekoekslaan 1, 3435 CM, Nieuwegein, The Netherlands aut NATIONALLICENCE 700 1- Verzijlbergen Fred Department of Nuclear Cardiology, St Antonius Hospital, Koekoekslaan 1, 3435 CM, Nieuwegein, The Netherlands aut NATIONALLICENCE 700 1- Zwindermans Aelko Department of Medical Statistics, University of Leiden, Niels Bohrweg 1, 2333 CL, Leiden, The Netherlands aut NATIONALLICENCE 700 1- Ascoop Carl Department of Cardiology, St Antonius Hospital, Koekoekslaan 1, 3435 CM, Nieuwegein, The Netherlands aut NATIONALLICENCE 700 1- Pauwels Ernest Department of Diagnostic Radiology, University Hospital, Rijnsburgerweg 10, 2333 AA, Leiden, The Netherlands aut NATIONALLICENCE 773 0- European Journal of Nuclear Medicine Springer-Verlag 16/8-10(1990-08-01), 697-704 0340-6997 16:8-10<697 1990 16 259 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer