caa a22 4500 465786189 CHVBK 20180323112009.0 cr unu---uuuuu 170327e19900801xx s 000 0 eng 10.1007/BF00998183 doi (NATIONALLICENCE)springer-10.1007/BF00998183 Association between false negative hepatobiliary scans and initial gallbladder visualization after 30 min [Elektronische Daten] [Rodney Hicks, Michael Kelly, Victor Kalff] We have reviewed the experience of our institution and the literature concerning the use of hepatobiliary scintigraphy for the diagnosis of acute cholecystitis. The aim of this study was to assess whether the hepatobiliary scintigraphic finding of initial gallbladder visualization within 30 min is a more reliable criterion for excluding acute cholecystitis than gallbladder visualization within 1 h after tracer injection. In our institution's consecutive series, 113 of 211 hepatobiliary studies had gallbladder visualization within 1 h. Gallbladder visualization time in this group had a log normal distribution, with gallbladder visualization occurring within 30 min in 107 of 113 (95%). Gallbladder visualization occurred between 31 and 60 min in only 6 (5%); nevertheless, our one false negative study came from this small subgroup of patient studies (P = 0.05). Review of the literature (1645 patients with iminodiacetic acid [99mTc-IDA] derivative studies) revealed 6 further timed false negative results with gallbladder visualization within 1 h. Of these studies, in 4 (67%) the gallbladder was visualized between 31 and 60 min and in only 2 before 30 min. One of these latter 2 patients had a rare anatomy. Analysis of the pooled institutional and literature data gave an estimated false negative rate of 21 % if the gallbladder was visualized between 31 and 60 min. This was significantly higher (P < 0.001) than the 0.5% false negative rate when the gallbladder was seen prior to 30 min, but similar to the false negative rate of 16% reported by Weissmann et al. for studies with initial visualization after 1 h. Therefore, gallbladder visualization is strong evidence against acute cholecystitis only if it occurs within 30 min after tracer injection. Springer-Verlag, 1990 Hepatobiliary scintigraphy nationallicence Acute cholecystitis nationallicence Hicks Rodney Department of Nuclear Medicine, Alfred Hospital, Commercial Rd, 3181, Melbourne, Victoria, Australia aut Kelly Michael Department of Nuclear Medicine, Alfred Hospital, Commercial Rd, 3181, Melbourne, Victoria, Australia aut Kalff Victor Department of Nuclear Medicine, Alfred Hospital, Commercial Rd, 3181, Melbourne, Victoria, Australia aut European Journal of Nuclear Medicine Springer-Verlag 16/8-10(1990-08-01), 747-753 0340-6997 16:8-10<747 1990 16 259 https://doi.org/10.1007/BF00998183 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00998183 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hicks Rodney Department of Nuclear Medicine, Alfred Hospital, Commercial Rd, 3181, Melbourne, Victoria, Australia aut NATIONALLICENCE 700 1- Kelly Michael Department of Nuclear Medicine, Alfred Hospital, Commercial Rd, 3181, Melbourne, Victoria, Australia aut NATIONALLICENCE 700 1- Kalff Victor Department of Nuclear Medicine, Alfred Hospital, Commercial Rd, 3181, Melbourne, Victoria, Australia aut NATIONALLICENCE 773 0- European Journal of Nuclear Medicine Springer-Verlag 16/8-10(1990-08-01), 747-753 0340-6997 16:8-10<747 1990 16 259 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer