caa a22 4500 465786278 CHVBK 20180323112010.0 cr unu---uuuuu 170327e19900801xx s 000 0 eng 10.1007/BF00998155 doi (NATIONALLICENCE)springer-10.1007/BF00998155 Error of uptake in dual energy acquisition with201TI and123I labeled radiopharmaceuticals [Elektronische Daten] [Kenichi Nakajima, Junichi Taki, Hisashi Bunko, Masami Shimizu, Akira Muramori, Norihisa Tonami, Kinichi Hisada] In myocardial scintigraphy, simultaneous injection of two radionuclides and dual energy acquisition are potentially useful in the assessment of regional perfusion and metabolism. The feasibility of dual radionuclide study with201TI and123I labeled radiopharmaceuticals (meta-iodobenzylguanidine I 123, in this study) was investigated in phantoms and patients. The crosstalk of one radionuclide to the other pulse height window was defined as the ratio of the201T1 count in the123I and201T1 windows, R[I/Tl], and the ratio of the123I count in the201TI and123I windows, R[Tl/I]. The ratios were determined in planar images and SPECT studies. In clinical studies with whole body scintigraphy (n = 8), the value of R differed significantly in various organs. In the SPECT study (n =13), R was not uniform and varied with time and location, resulting in significant errors in uptake and regional count ratio. Thus, dual energy acquisition with201TI and 1231 labeled radiopharmaceuticals is generally not recommended because of varying amounts of crosstalk interference. Possible solutions to this problem are discussed. The feasibility of dual radionuclide study must be confirmed in human as well as in phantom studies. Springer-Verlag, 1990 Myocardial scintigraphy nationallicence Compton scatter nationallicence Dual energy acquisition nationallicence 201T1 nationallicence 123I nationallicence Nakajima Kenichi Department of Nuclear Medicine, Kanazawa University School of Medicine, 13-1 Takara-machi, 920, Kanazawa, Japan aut Taki Junichi Department of Nuclear Medicine, Kanazawa University School of Medicine, 13-1 Takara-machi, 920, Kanazawa, Japan aut Bunko Hisashi Department of Nuclear Medicine, Kanazawa University School of Medicine, 13-1 Takara-machi, 920, Kanazawa, Japan aut Shimizu Masami Second Department of Internal Medicine, Kanazawa University School of Medicine, 13-1 Takara-machi, 920, Kanazawa, Japan aut Muramori Akira Department of Nuclear Medicine, Kanazawa University School of Medicine, 13-1 Takara-machi, 920, Kanazawa, Japan aut Tonami Norihisa Department of Nuclear Medicine, Kanazawa University School of Medicine, 13-1 Takara-machi, 920, Kanazawa, Japan aut Hisada Kinichi Department of Nuclear Medicine, Kanazawa University School of Medicine, 13-1 Takara-machi, 920, Kanazawa, Japan aut European Journal of Nuclear Medicine Springer-Verlag 16/8-10(1990-08-01), 595-599 0340-6997 16:8-10<595 1990 16 259 https://doi.org/10.1007/BF00998155 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00998155 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Nakajima Kenichi Department of Nuclear Medicine, Kanazawa University School of Medicine, 13-1 Takara-machi, 920, Kanazawa, Japan aut NATIONALLICENCE 700 1- Taki Junichi Department of Nuclear Medicine, Kanazawa University School of Medicine, 13-1 Takara-machi, 920, Kanazawa, Japan aut NATIONALLICENCE 700 1- Bunko Hisashi Department of Nuclear Medicine, Kanazawa University School of Medicine, 13-1 Takara-machi, 920, Kanazawa, Japan aut NATIONALLICENCE 700 1- Shimizu Masami Second Department of Internal Medicine, Kanazawa University School of Medicine, 13-1 Takara-machi, 920, Kanazawa, Japan aut NATIONALLICENCE 700 1- Muramori Akira Department of Nuclear Medicine, Kanazawa University School of Medicine, 13-1 Takara-machi, 920, Kanazawa, Japan aut NATIONALLICENCE 700 1- Tonami Norihisa Department of Nuclear Medicine, Kanazawa University School of Medicine, 13-1 Takara-machi, 920, Kanazawa, Japan aut NATIONALLICENCE 700 1- Hisada Kinichi Department of Nuclear Medicine, Kanazawa University School of Medicine, 13-1 Takara-machi, 920, Kanazawa, Japan aut NATIONALLICENCE 773 0- European Journal of Nuclear Medicine Springer-Verlag 16/8-10(1990-08-01), 595-599 0340-6997 16:8-10<595 1990 16 259 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer