caa a22 4500 465787207 CHVBK 20180323112012.0 cr unu---uuuuu 170327e19901001xx s 000 0 eng 10.1007/BF00294097 doi (NATIONALLICENCE)springer-10.1007/BF00294097 Sedimentation study on the binding of fibrinogen or of antithrombin III with acidic polysaccharides including heparin [Elektronische Daten] [Eiji Nakanishi, Hiroko Sato, Akio Nakajima] Summary: The binding of fibrinogen with heparin and dextran sulfates, and of antithrombin III with heparin and dextran sulfate were investigated by sedimentation velocity method. From the measurement of fibrinogen-acidic polysaccharide systems, it was confirmed that heparin and low molecular weight dextran sulfate(DSC) forms soluble complexes with fibrinogen, though the amount bound of the latter was rather small compared with high molecular weight dextran sulfate(DSD). Antithrombin III was also found to be bound by heparin and DSC. The numbers of heparin molecules bound to one molecule of fibrinogen and antithrombin III were estimated to be 4.2 and 0.3, respectively. Springer-Verlag, 1990 Nakanishi Eiji Department of Polymer Chemistry, Faculty of Engineering, Kyoto University, Sakyo-ku, 606, Kyoto, Japan aut Sato Hiroko Department of Polymer Chemistry, Faculty of Engineering, Kyoto University, Sakyo-ku, 606, Kyoto, Japan aut Nakajima Akio Department of Polymer Chemistry, Faculty of Engineering, Kyoto University, Sakyo-ku, 606, Kyoto, Japan aut Polymer Bulletin Springer-Verlag 24/4(1990-10-01), 429-435 0170-0839 24:4<429 1990 24 289 https://doi.org/10.1007/BF00294097 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00294097 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Nakanishi Eiji Department of Polymer Chemistry, Faculty of Engineering, Kyoto University, Sakyo-ku, 606, Kyoto, Japan aut NATIONALLICENCE 700 1- Sato Hiroko Department of Polymer Chemistry, Faculty of Engineering, Kyoto University, Sakyo-ku, 606, Kyoto, Japan aut NATIONALLICENCE 700 1- Nakajima Akio Department of Polymer Chemistry, Faculty of Engineering, Kyoto University, Sakyo-ku, 606, Kyoto, Japan aut NATIONALLICENCE 773 0- Polymer Bulletin Springer-Verlag 24/4(1990-10-01), 429-435 0170-0839 24:4<429 1990 24 289 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer