caa a22 4500 465789668 CHVBK 20180323112019.0 cr unu---uuuuu 170327e19900801xx s 000 0 eng 10.1007/BF00171842 doi (NATIONALLICENCE)springer-10.1007/BF00171842 A phase II study of mitoxantrone in advanced gastric cancer [Elektronische Daten] [J. Levi, P. Gill, P. Presgrave] Summary: Sixteen patients with advanced adenocarcinoma of the stomach were entered into a phase II study of mitoxantrone at a dosage of either 12 mg/m2 or 14 mg/m2 given at 3 weekly intervals. Nine patients had received prior chemotherapy including doxorubicin. No patients achieved either a complete or partial response, five patients had stable disease and the remainder disease progression. Moderate to severe leukopenia occurred in 10 patients with one septic death. Median survival for all patients was eight weeks (range 1-49 weeks). It is concluded that mitoxantrone has no worthwhile activity in gastric cancer at the described doses. Kluwer Academic Publishers, 1990 mitoxantrone nationallicence gastric cancer nationallicence phase II nationallicence Levi J. Department of Clinical Oncology, Royal North Shore Hospital of Sydney, Sydney, Australia aut Gill P. Department of Surgery, Royal Adelaide Hospital, Adelaide, Australia aut Presgrave P. Department of Clinical Oncology, Royal North Shore Hospital of Sydney, Sydney, Australia aut Investigational New Drugs Kluwer Academic Publishers 8/3(1990-08-01), 305-306 0167-6997 8:3<305 1990 8 10637 https://doi.org/10.1007/BF00171842 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00171842 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Levi J. Department of Clinical Oncology, Royal North Shore Hospital of Sydney, Sydney, Australia aut NATIONALLICENCE 700 1- Gill P. Department of Surgery, Royal Adelaide Hospital, Adelaide, Australia aut NATIONALLICENCE 700 1- Presgrave P. Department of Clinical Oncology, Royal North Shore Hospital of Sydney, Sydney, Australia aut NATIONALLICENCE 773 0- Investigational New Drugs Kluwer Academic Publishers 8/3(1990-08-01), 305-306 0167-6997 8:3<305 1990 8 10637 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer