caa a22 4500 465794637 CHVBK 20180323112034.0 cr unu---uuuuu 170327e19900801xx s 000 0 eng 10.1007/BF00142588 doi (NATIONALLICENCE)springer-10.1007/BF00142588 The effect of iodoacetic acid on the electroretinogram and oscillatory potentials in rabbits [Elektronische Daten] [Pierre Lachapelle, Julie Benoit, Pierre Guité, Cuong Tran, Stéphane Molotchnikoff] It has been shown that a single injection of iodoacetic acid selectively (but temporarily) abolishes the b-wave of the electroretinogram. We examined whether such use of this chemical further substantiate our claim that the b-wave of the electroretinogram is a composite potential resulting from the summation (or integration) of faster retinal potentials, usually referred to as the oscillatory potentials. Full-field electroretinograms were recorded from adult New Zealand rabbits before and after a single, bolus injection of 15mg/kg of buffered iodoacetic acid. Both the 1-1000 Hz electroretinogram and the 100-1000 Hz oscillatory potentials were recorded simultaneously. The oscillatory potentials considered in this study were those normally seen on the rising phase of the b-wave. Following the intravenous injection of iodoacetic acid, there was a progressive decrease in the amplitude and peak time of the b-wave. This observation also was reflected in the oscillatory potential recordings, in which the long-latency oscillatory potentials (3 and 4) progressively disappeared while oscillatory potential 2 remained. We believe that these findings further support our contention that the oscillatory potentials are major components of the b-wave. Kluwer Academic Publishers, 1990 electroretinogram nationallicence iodoacetic acid nationallicence oscillatory potentials nationallicence rabbit nationallicence Lachapelle Pierre Department of Ophthalmology, McGill University - Montreal Children's Hospital Research Institute, Montreal, Canada aut Benoit Julie Department of Neurology-Neurosurgery, McGill University - Montreal Children's Hospital Research Institute, Montreal, Canada aut Guité Pierre Department of Neurology-Neurosurgery, McGill University - Montreal Children's Hospital Research Institute, Montreal, Canada aut Tran Cuong Faculty of Medicine, McGill University - Montreal Children's Hospital Research Institute, Montreal, Canada aut Molotchnikoff Stéphane Département de Sciences Biologiques, Université de Montréal, Montreal, Canada aut Documenta Ophthalmologica Kluwer Academic Publishers 75/1(1990-08-01), 7-14 0012-4486 75:1<7 1990 75 10633 https://doi.org/10.1007/BF00142588 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00142588 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lachapelle Pierre Department of Ophthalmology, McGill University - Montreal Children's Hospital Research Institute, Montreal, Canada aut NATIONALLICENCE 700 1- Benoit Julie Department of Neurology-Neurosurgery, McGill University - Montreal Children's Hospital Research Institute, Montreal, Canada aut NATIONALLICENCE 700 1- Guité Pierre Department of Neurology-Neurosurgery, McGill University - Montreal Children's Hospital Research Institute, Montreal, Canada aut NATIONALLICENCE 700 1- Tran Cuong Faculty of Medicine, McGill University - Montreal Children's Hospital Research Institute, Montreal, Canada aut NATIONALLICENCE 700 1- Molotchnikoff Stéphane Département de Sciences Biologiques, Université de Montréal, Montreal, Canada aut NATIONALLICENCE 773 0- Documenta Ophthalmologica Kluwer Academic Publishers 75/1(1990-08-01), 7-14 0012-4486 75:1<7 1990 75 10633 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer