caa a22 4500 465794688 CHVBK 20180323112034.0 cr unu---uuuuu 170327e19900801xx s 000 0 eng 10.1007/BF00142589 doi (NATIONALLICENCE)springer-10.1007/BF00142589 L-cystein protects the pigment epithelium from acute sodium iodate toxicity [Elektronische Daten] [Minako Heike, Michael Marmor] Intravenous sodium iodate damages the retinal pigment epithelium, causing immediate loss of the electroretinogram c-wave and eventual pigmentary retinopathy. L-cystein, an agent that enhances the c-wave, has been reported to prevent the late development of pigmentary degeneration. We found in rabbits that L-cystein given 30 min before, or simultaneously with (but not 30 min after) sodium iodate also blocks the loss of the c-wave. This result occurred at doses of L-cystein lower than those needed to produce enhancement of the c-wave, suggesting that these two actions of L-cystein may be independent. The iodate-blocking action of L-cystein may depend on chemical interaction. Kluwer Academic Publishers, 1990 c-wave nationallicence L-cystein nationallicence retinal degeneration nationallicence retinal pigment epithelium nationallicence sodium iodate nationallicence Heike Minako Department of Ophthalmology, Stanford University School of Medicine, Stanford, California, USA aut Marmor Michael Department of Ophthalmology, Stanford University School of Medicine, Stanford, California, USA aut Documenta Ophthalmologica Kluwer Academic Publishers 75/1(1990-08-01), 15-22 0012-4486 75:1<15 1990 75 10633 https://doi.org/10.1007/BF00142589 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00142589 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Heike Minako Department of Ophthalmology, Stanford University School of Medicine, Stanford, California, USA aut NATIONALLICENCE 700 1- Marmor Michael Department of Ophthalmology, Stanford University School of Medicine, Stanford, California, USA aut NATIONALLICENCE 773 0- Documenta Ophthalmologica Kluwer Academic Publishers 75/1(1990-08-01), 15-22 0012-4486 75:1<15 1990 75 10633 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer